• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Methotrexate and TNF inhibitors affect long-term immunogenicity to COVID-19 vaccination in patients with immune-mediated inflammatory disease.

作者信息

Haberman Rebecca H, Um Seungha, Axelrad Jordan E, Blank Rebecca B, Uddin Zakwan, Catron Sydney, Neimann Andrea L, Mulligan Mark J, Herat Ramin Sedaghat, Hong Simon J, Chang Shannon, Myrtaj Arnold, Ghiasian Ghoncheh, Izmirly Peter M, Saxena Amit, Solomon Gary, Azar Natalie, Samuels Jonathan, Golden Brian D, Rackoff Paula, Adhikari Samrachana, Hudesman David P, Scher Jose U

机构信息

Division of Rheumatology, Department of Medicine, NYU Grossman School of Medicine, New York, NY 10016, USA.

Department of Population Health, New York University Langone Health, New York, NY, USA.

出版信息

Lancet Rheumatol. 2022 Jun;4(6):e384-e387. doi: 10.1016/S2665-9913(22)00069-8. Epub 2022 Apr 1.

DOI:10.1016/S2665-9913(22)00069-8
PMID:35403000
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8975261/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fccc/8975261/0c3730976257/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fccc/8975261/0c3730976257/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fccc/8975261/0c3730976257/gr1_lrg.jpg

相似文献

1
Methotrexate and TNF inhibitors affect long-term immunogenicity to COVID-19 vaccination in patients with immune-mediated inflammatory disease.甲氨蝶呤和肿瘤坏死因子抑制剂会影响免疫介导的炎症性疾病患者对新冠疫苗接种的长期免疫原性。
Lancet Rheumatol. 2022 Jun;4(6):e384-e387. doi: 10.1016/S2665-9913(22)00069-8. Epub 2022 Apr 1.
2
Methotrexate Hampers Immunogenicity to BNT162b2 mRNA COVID-19 Vaccine in Immune-Mediated Inflammatory Disease.甲氨蝶呤会削弱免疫介导的炎症性疾病患者对BNT162b2 mRNA新冠疫苗的免疫原性。
medRxiv. 2021 May 12:2021.05.11.21256917. doi: 10.1101/2021.05.11.21256917.
3
Association Between Tumor Necrosis Factor Inhibitors and the Risk of Hospitalization or Death Among Patients With Immune-Mediated Inflammatory Disease and COVID-19.肿瘤坏死因子抑制剂与 COVID-19 合并免疫介导的炎症性疾病患者住院或死亡风险的相关性。
JAMA Netw Open. 2021 Oct 1;4(10):e2129639. doi: 10.1001/jamanetworkopen.2021.29639.
4
Antibody Response to SARS-CoV-2 Vaccination in Patients with Inflammatory Bowel Disease: Results of a Single-Center Cohort Study in a Tertiary Hospital in Germany.德国一家三级医院的单中心队列研究:炎症性肠病患者对 SARS-CoV-2 疫苗接种的抗体反应。
Dig Dis. 2022;40(6):719-727. doi: 10.1159/000521343. Epub 2021 Dec 10.
5
Anti-SARS-CoV-2 Vaccination and Antibody Response in Patients With Inflammatory Bowel Disease on Immune-modifying Therapy: Prospective Single-Tertiary Study.抗 SARS-CoV-2 疫苗接种和免疫调节治疗的炎症性肠病患者的抗体反应:前瞻性单中心研究。
Inflamm Bowel Dis. 2022 Oct 3;28(10):1506-1512. doi: 10.1093/ibd/izab301.
6
Short and long-term immunogenicity and safety following the 23-valent polysaccharide pneumococcal vaccine in juvenile idiopathic arthritis patients under conventional DMARDs with or without anti-TNF therapy.在接受或未接受抗TNF治疗的传统改善病情抗风湿药治疗的幼年特发性关节炎患者中,接种23价肺炎球菌多糖疫苗后的短期和长期免疫原性及安全性。
Vaccine. 2015 Jan 29;33(5):604-9. doi: 10.1016/j.vaccine.2014.12.030. Epub 2014 Dec 29.
7
Immunogenicity of BNT162b2 mRNA SARS-CoV-2 vaccine in patients with psoriatic arthritis on TNF inhibitors.接受 TNF 抑制剂治疗的银屑病关节炎患者中 BNT162b2 mRNA SARS-CoV-2 疫苗的免疫原性。
RMD Open. 2022 Jan;8(1). doi: 10.1136/rmdopen-2021-001847.
8
An Argentinean cohort of patients with rheumatic and immune-mediated diseases vaccinated for SARS-CoV-2: the SAR-CoVAC Registry-protocol and preliminary data.一项针对风湿和免疫介导性疾病患者的阿根廷队列研究:SARS-CoV-2 疫苗接种:SAR-CoVAC 注册研究方案和初步数据。
Clin Rheumatol. 2022 Oct;41(10):3199-3209. doi: 10.1007/s10067-022-06253-5. Epub 2022 Jun 28.
9
Antibody response is reduced following vaccination with 7-valent conjugate pneumococcal vaccine in adult methotrexate-treated patients with established arthritis, but not those treated with tumor necrosis factor inhibitors.在患有确诊关节炎的成年甲氨蝶呤治疗患者中,接种7价结合肺炎球菌疫苗后抗体反应降低,但接受肿瘤坏死因子抑制剂治疗的患者则不然。
Arthritis Rheum. 2011 Dec;63(12):3723-32. doi: 10.1002/art.30580.
10
Serological response to SARS-CoV-2 vaccination in patients with inflammatory rheumatic disease treated with disease modifying anti-rheumatic drugs: A cohort study and a meta-analysis.炎症性风湿病患者在使用疾病修正抗风湿药物治疗的情况下对 SARS-CoV-2 疫苗接种的血清学反应:一项队列研究和荟萃分析。
Joint Bone Spine. 2022 Oct;89(5):105380. doi: 10.1016/j.jbspin.2022.105380. Epub 2022 Apr 28.

引用本文的文献

1
Methotrexate treatment hampers induction of vaccine-specific CD4 T cell responses in patients with IMID.甲氨蝶呤治疗阻碍了 IMID 患者疫苗特异性 CD4 T 细胞应答的诱导。
RMD Open. 2024 Oct 7;10(4):e004664. doi: 10.1136/rmdopen-2024-004664.
2
Impact of Immunomodulatory Therapy on COVID-19 Vaccine Response in Patients with Autoimmune Inflammatory Rheumatic Diseases.免疫调节治疗对自身免疫性炎性风湿病患者新冠病毒疫苗反应的影响
Vaccines (Basel). 2024 Mar 6;12(3):274. doi: 10.3390/vaccines12030274.
3
Three doses of COVID-19 mRNA vaccine induce class-switched antibody responses in inflammatory arthritis patients on immunomodulatory therapies.

本文引用的文献

1
Large-Scale Study of Antibody Titer Decay following BNT162b2 mRNA Vaccine or SARS-CoV-2 Infection.BNT162b2 mRNA疫苗接种或SARS-CoV-2感染后抗体滴度衰减的大规模研究
Vaccines (Basel). 2021 Dec 31;10(1):64. doi: 10.3390/vaccines10010064.
2
Reduced antibody activity against SARS-CoV-2 B.1.617.2 delta virus in serum of mRNA-vaccinated individuals receiving tumor necrosis factor-α inhibitors.mRNA 疫苗接种者在接受肿瘤坏死因子-α 抑制剂治疗后血清中针对 SARS-CoV-2 B.1.617.2 德尔塔病毒的抗体活性降低。
Med. 2021 Dec 10;2(12):1327-1341.e4. doi: 10.1016/j.medj.2021.11.004. Epub 2021 Nov 18.
3
Waning Immune Humoral Response to BNT162b2 Covid-19 Vaccine over 6 Months.
COVID-19 mRNA 疫苗三剂可诱导免疫调节治疗的炎症性关节炎患者发生类别转换抗体应答。
Front Immunol. 2023 Oct 24;14:1266370. doi: 10.3389/fimmu.2023.1266370. eCollection 2023.
4
Impact of methotrexate on humoral and cellular immune responses to SARS-CoV-2 mRNA vaccine in patients with rheumatoid arthritis.甲氨蝶呤对类风湿关节炎患者新冠病毒 mRNA 疫苗体液和细胞免疫应答的影响。
Clin Exp Med. 2023 Dec;23(8):4707-4720. doi: 10.1007/s10238-023-01163-5. Epub 2023 Aug 16.
5
TNF inhibitors significantly attenuate the humoral immune response to COVID-19 vaccination in patients with rheumatoid arthritis.肿瘤坏死因子抑制剂可显著减弱类风湿性关节炎患者对新冠病毒疫苗接种的体液免疫反应。
Rheumatol Adv Pract. 2023 Jul 26;7(2):rkad065. doi: 10.1093/rap/rkad065. eCollection 2023.
6
Managing Immunosuppression in Vasculitis Patients in Times of Coronavirus Disease 2019.COVID-19 时期血管炎患者的免疫抑制管理。
Rheum Dis Clin North Am. 2023 Aug;49(3):695-711. doi: 10.1016/j.rdc.2023.03.007. Epub 2023 Mar 14.
7
Determinants of COVID-19 Disease Severity-Lessons from Primary and Secondary Immune Disorders including Cancer.COVID-19 疾病严重程度的决定因素——包括癌症在内的原发性和继发性免疫紊乱的教训。
Int J Mol Sci. 2023 May 14;24(10):8746. doi: 10.3390/ijms24108746.
8
The effects of methotrexate on the immune responses to the COVID-19 vaccines in the patients with immune-mediated inflammatory disease: A systematic review of clinical evidence.甲氨蝶呤对免疫介导的炎症性疾病患者 COVID-19 疫苗免疫反应的影响:临床证据的系统评价。
Transpl Immunol. 2023 Aug;79:101858. doi: 10.1016/j.trim.2023.101858. Epub 2023 May 24.
9
Primary SARS-CoV-2 infection in patients with immune-mediated inflammatory diseases: long-term humoral immune responses and effects on disease activity.原发性 SARS-CoV-2 感染在免疫介导的炎症性疾病患者中的情况:长期体液免疫反应及其对疾病活动的影响。
BMC Infect Dis. 2023 May 17;23(1):332. doi: 10.1186/s12879-023-08298-6.
10
Persistence of SARS-CoV-2 neutralizing antibodies and anti-Omicron IgG induced by BNT162b2 mRNA vaccine in patients with autoimmune inflammatory rheumatic disease: an explanatory study in Japan.BNT162b2 mRNA疫苗诱导的自身免疫性炎性风湿病患者中SARS-CoV-2中和抗体及抗奥密克戎IgG的持久性:日本的一项解释性研究
Lancet Reg Health West Pac. 2023 Mar;32:100661. doi: 10.1016/j.lanwpc.2022.100661. Epub 2022 Dec 20.
辉瑞-BioNTech 新冠疫苗接种 6 个月后免疫体液反应逐渐减弱。
N Engl J Med. 2021 Dec 9;385(24):e84. doi: 10.1056/NEJMoa2114583. Epub 2021 Oct 6.
4
Immunogenicity and safety of the BNT162b2 mRNA COVID-19 vaccine in adult patients with autoimmune inflammatory rheumatic diseases and in the general population: a multicentre study.BNT162b2 mRNA COVID-19 疫苗在成年自身免疫性炎症性风湿病患者和普通人群中的免疫原性和安全性:一项多中心研究。
Ann Rheum Dis. 2021 Oct;80(10):1330-1338. doi: 10.1136/annrheumdis-2021-220647. Epub 2021 Jun 14.
5
Methotrexate hampers immunogenicity to BNT162b2 mRNA COVID-19 vaccine in immune-mediated inflammatory disease.甲氨蝶呤会削弱免疫介导的炎症性疾病患者对BNT162b2 mRNA新冠疫苗的免疫原性。
Ann Rheum Dis. 2021 Oct;80(10):1339-1344. doi: 10.1136/annrheumdis-2021-220597. Epub 2021 May 25.
6
High antibody response to two-dose SARS-CoV-2 messenger RNA vaccination in patients with rheumatic and musculoskeletal diseases.风湿性和肌肉骨骼疾病患者对两剂严重急性呼吸综合征冠状病毒2信使核糖核酸疫苗的高抗体反应。
Ann Rheum Dis. 2021 Oct;80(10):1351-1352. doi: 10.1136/annrheumdis-2021-220656. Epub 2021 May 24.
7
Antibody Response to Hepatitis B Virus Vaccine is Impaired in Patients With Inflammatory Bowel Disease on Infliximab Therapy.英夫利昔单抗治疗的炎症性肠病患者对乙型肝炎病毒疫苗的抗体反应受损。
Inflamm Bowel Dis. 2018 Jan 18;24(2):380-386. doi: 10.1093/ibd/izx001.
8
Immunogenicity and Safety of Influenza Vaccine in Inflammatory Bowel Disease Patients Treated or not with Immunomodulators and/or Biologics: A Two-year Prospective Study.免疫调节剂和/或生物制剂治疗或未治疗的炎症性肠病患者流感疫苗的免疫原性和安全性:一项为期两年的前瞻性研究。
J Crohns Colitis. 2015 Dec;9(12):1096-107. doi: 10.1093/ecco-jcc/jjv152. Epub 2015 Sep 7.
9
Effect of methotrexate, anti-tumor necrosis factor α, and rituximab on the immune response to influenza and pneumococcal vaccines in patients with rheumatoid arthritis: a systematic review and meta-analysis.甲氨蝶呤、肿瘤坏死因子-α 拮抗剂和利妥昔单抗对类风湿关节炎患者流感和肺炎球菌疫苗免疫应答的影响:系统评价和荟萃分析。
Arthritis Care Res (Hoboken). 2014 Jul;66(7):1016-26. doi: 10.1002/acr.22246.