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From genome editing to blastocyst complementation: A new horizon in heart transplantation?

作者信息

Konstantinov Igor E, King Gregory, Porrello Enzo R

机构信息

Department of Cardiac Surgery, Royal Children's Hospital, Melbourne, Victoria, Australia.

Department of Paediatrics, The University of Melbourne, Melbourne, Victoria, Australia.

出版信息

JTCVS Tech. 2022 Jan 21;12:177-184. doi: 10.1016/j.xjtc.2022.01.012. eCollection 2022 Apr.

DOI:10.1016/j.xjtc.2022.01.012
PMID:35403039
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8987386/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/607a/8987386/6f1fc0b24d91/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/607a/8987386/67228de3cf39/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/607a/8987386/126b5ea58c95/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/607a/8987386/a08cdefc1dae/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/607a/8987386/ba0e27a9708c/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/607a/8987386/6f1fc0b24d91/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/607a/8987386/67228de3cf39/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/607a/8987386/126b5ea58c95/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/607a/8987386/a08cdefc1dae/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/607a/8987386/ba0e27a9708c/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/607a/8987386/6f1fc0b24d91/gr4.jpg

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本文引用的文献

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First pig-to-human heart transplant: what can scientists learn?首例猪心脏移植到人体：科学家能学到什么？
Nature. 2022 Jan;601(7893):305-306. doi: 10.1038/d41586-022-00111-9.
2
Recent advances on bioengineering approaches for fabrication of functional engineered cardiac pumps: A review.生物工程方法在功能性工程心脏泵制造中的最新进展：综述。
Biomaterials. 2022 Jan;280:121298. doi: 10.1016/j.biomaterials.2021.121298. Epub 2021 Nov 30.
3
Generation of Organs by Blastocyst Complementation: Advances and Challenges.通过囊胚互补生成器官：进展与挑战
Int J Stem Cells. 2022 May 30;15(2):113-121. doi: 10.15283/ijsc21122.
4
Bioengineering approaches to treat the failing heart: from cell biology to 3D printing.生物工程方法治疗心力衰竭：从细胞生物学到 3D 打印。
Nat Rev Cardiol. 2022 Feb;19(2):83-99. doi: 10.1038/s41569-021-00603-7. Epub 2021 Aug 27.
5
National Trends in Heart Donor Usage Rates: Are We Efficiently Transplanting More Hearts?全国范围内心脏供体使用率的变化趋势：我们是否有效地移植了更多的心脏？
J Am Heart Assoc. 2021 Aug 3;10(15):e019655. doi: 10.1161/JAHA.120.019655. Epub 2021 Jul 28.
6
Chimeric contribution of human extended pluripotent stem cells to monkey embryos ex vivo.人源扩展多能干细胞对体外猴胚胎的嵌合贡献。
Cell. 2021 Apr 15;184(8):2020-2032.e14. doi: 10.1016/j.cell.2021.03.020.
7
The NIH Somatic Cell Genome Editing program.美国国立卫生研究院体细胞基因组编辑计划。
Nature. 2021 Apr;592(7853):195-204. doi: 10.1038/s41586-021-03191-1. Epub 2021 Apr 7.
8
Autologous Induced Pluripotent Stem Cell-Based Cell Therapies: Promise, Progress, and Challenges.基于自体诱导多能干细胞的细胞疗法：前景、进展和挑战。
Curr Protoc. 2021 Mar;1(3):e88. doi: 10.1002/cpz1.88.
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Human Engineered Heart Tissue Patches Remuscularize the Injured Heart in a Dose-Dependent Manner.人源化心脏组织补片以剂量依赖的方式使受损心脏重获肌肉。
Circulation. 2021 May 18;143(20):1991-2006. doi: 10.1161/CIRCULATIONAHA.120.047904. Epub 2021 Mar 2.
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Persistence of intramyocardially transplanted murine induced pluripotent stem cell-derived cardiomyocytes from different developmental stages.不同发育阶段的心肌内移植小鼠诱导多能干细胞衍生心肌细胞的持久性。
Stem Cell Res Ther. 2021 Jan 8;12(1):46. doi: 10.1186/s13287-020-02089-5.