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特发性炎性肌病皮肤表现的最新进展及其在皮肌炎诊断中的作用

Update on Cutaneous Signs to Assist in the Diagnosis of Dermatomyositis.

机构信息

Department of Dermatology, Stanford University School of Medicine, 450 Broadway, Pavilion C #C-234, Redwood City, CA, 94063, USA.

出版信息

Curr Rheumatol Rep. 2022 May;24(5):156-165. doi: 10.1007/s11926-022-01070-w. Epub 2022 Apr 11.

DOI:10.1007/s11926-022-01070-w
PMID:35404005
Abstract

PURPOSE OF REVIEW

Dermatomyositis (DM) is a heterogeneous idiopathic inflammatory myopathy that can be challenging to diagnose. Learning about the cutaneous manifestations in DM can assist with prompt diagnosis as well as subgroup classification. This review highlights recent data regarding cutaneous signs in DM and their associations with myositis-specific antibodies (MSAs).

RECENT FINDINGS

Several novel DM skin signs have recently been reported. Novel and confirmatory data have helped to define more clearly the associations between various cutaneous manifestations and MSAs. Awareness of the diverse cutaneous phenotypes can help with the timely diagnosis of DM. As some MSAs are associated with atypical skin features and/or characteristic patterns of clinical findings, knowledge of these associations can help clinicians to recognize DM patients. Understanding how the prevalence and presentation of various cutaneous signs differ among ethnically diverse patients is a high priority for further study.

摘要

目的综述

皮肌炎(DM)是一种异质性特发性炎症性肌病,诊断具有一定挑战性。了解 DM 的皮肤表现有助于及时诊断和亚组分类。本综述重点介绍了 DM 皮肤表现及其与肌炎特异性抗体(MSA)的最新关联。

最近的发现

最近报道了几种新的 DM 皮肤征象。新的和证实的数据有助于更清楚地定义各种皮肤表现与 MSA 之间的关联。了解不同的皮肤表型有助于及时诊断 DM。由于一些 MSA 与非典型皮肤特征和/或特征性临床发现模式相关,因此了解这些关联可以帮助临床医生识别 DM 患者。了解不同种族患者中各种皮肤征象的患病率和表现存在差异是进一步研究的重点。

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