Department of Cardiology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200 Aarhus N, Denmark.
Department of Heart Disease, Haukeland University Hospital, Box 1400, 5021 Bergen, Norway.
Eur J Cardiovasc Nurs. 2022 Nov 23;21(8):772-781. doi: 10.1093/eurjcn/zvac022.
Women report worse health-related patient-reported outcomes (PROs) compared with men following acute myocardial infarction (AMI). However, this association is not well established when accounting for demographic and clinical patient characteristics at discharge. This knowledge is essential for clinicians when planning individualised care for patients following AMI. The aim of this study is to examine whether gender is associated with health-related PROs at discharge from a Danish heart centre, combining PROs with data from the national health and administrative registries.
A cross-sectional study of 2131 patients with AMI discharged from a Danish heart centre responding to the following health-related PRO questionnaires: the Health-survey Short-Form-12 (SF-12), generating a physical component summary (PCS) and a mental component summary (MCS) score; the HeartQoL, providing a global, emotional, and physical score; the EuroQol five-dimensional questionnaire (EQ-5D-5L) and the EQ visual analogue scale (EQ VAS); the Hospital Anxiety and Depression Scale (HADS), generating an anxiety and depression score (HADS-A and HADS-D); the Edmonton Symptom Assessment Scale (ESAS); the Brief Illness Perception Questionnaire (B-IPQ). Patient-reported outcomes were linked to registry-based information adjusting for potential demographic and clinical confounding factors. In adjusted regression models, women reported worse health-related PROs compared with men in SF-12 PCS and SF-12 MCS, HeartQoL global, the HeartQoL emotional and HeartQoL physical score, EQ-5D-5L and EQ VAS, the HADS-A, ESAS, and in six out of eight B-IPQ items.
Women reported worse health-related PROs compared with men. Health-related PROs have the potential to be further investigated to facilitate a more individualised healthcare follow-up after AMI.
与急性心肌梗死（AMI）后男性相比，女性报告的健康相关患者报告结局（PRO）更差。然而，在考虑出院时的人口统计学和临床患者特征时，这种关联尚未得到很好的确立。当计划对 AMI 后患者进行个体化护理时，临床医生需要了解这方面的知识。本研究旨在通过结合健康相关 PRO 数据和国家健康及行政登记数据，检验丹麦心脏中心出院患者的性别与健康相关 PRO 之间是否存在相关性。
对丹麦心脏中心出院的 2131 例 AMI 患者进行了一项横断面研究，这些患者对以下健康相关 PRO 问卷做出了回应：健康调查简表-12 项（SF-12），生成身体成分综合评分（PCS）和精神成分综合评分（MCS）；心脏生活质量问卷（HeartQoL），提供总体、情感和身体评分；欧洲五维健康量表问卷（EQ-5D-5L）和 EQ 视觉模拟量表（EQ VAS）；医院焦虑抑郁量表（HADS），生成焦虑和抑郁评分（HADS-A 和 HADS-D）；埃德蒙顿症状评估量表（ESAS）；简短疾病感知问卷（B-IPQ）。将患者报告的结果与基于登记的信息相关联，并调整了潜在的人口统计学和临床混杂因素。在调整后的回归模型中，与男性相比，女性在 SF-12 PCS 和 SF-12 MCS、HeartQoL 总体、HeartQoL 情感和 HeartQoL 身体评分、EQ-5D-5L 和 EQ VAS、HADS-A、ESAS 和 B-IPQ 的八个项目中的六个项目中报告的健康相关 PRO 更差。
与男性相比，女性报告的健康相关 PRO 更差。健康相关 PRO 具有进一步研究的潜力，可促进 AMI 后更个体化的医疗保健随访。
