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骨质疏松性椎体骨折OF4的微创外科治疗选择

Minimally invasive surgical treatment options for osteoporotic vertebral fractures OF4.

作者信息

Burguet Girona S, Ferrando Meseguer E, Maruenda Paulino J I

机构信息

Unidad de Raquis, Servicio de Cirugía Ortopédica y Traumatología, Hospital Clínico Universitario, Valencia, España.

Unidad de Raquis, Servicio de Cirugía Ortopédica y Traumatología, Hospital Clínico Universitario, Valencia, España.

出版信息

Rev Esp Cir Ortop Traumatol. 2022 Mar-Apr;66(2):86-94. doi: 10.1016/j.recot.2021.07.009. Epub 2021 Nov 19.

Abstract

INTRODUCTION AND OBJECTIVE

The incidence of osteoporotic vertebral fractures (OVF) is increasing. The importance of their diagnosis and treatment lies in their frequency and the morbidity they cause in patients. The classification proposed for OVFs by the German Society of Orthopaedics and Traumatology (DGOU) recommends surgical treatment for vertebral fractures classified as OF4. Most of these fractures will require anterior bracing as an adjunct to posterior fixation because of the significant loss of vertebral body structure. In elderly patients, minimally invasive surgery (MIS) allows their treatment given the lesser tissue aggression and systemic repercussions. We present the results of the treatment of OF4 vertebral fractures using minimally invasive techniques in the Spine Unit of our hospital.

MATERIAL AND METHODS

Retrospective study of 21 patients with OF4 osteoporotic fractures in the thoracolumbar transition treated in our centre. Six patients who underwent open posterolateral fusion or isolated vertebroplasty were excluded. The series consists of 15 cases (13 females and 2 males), with a mean age of 72.2, studied by computed tomography and magnetic resonance imaging. Clinical and analytical data were collected to decide the most appropriate surgical technique. In six cases a retropleural/retroperitoneal MIS approach was performed for partial corpectomy with expandable vertebral substitute plus long posterior percutaneous fixation (technique 1). In the remaining nine cases long posterior percutaneous fixation + vertebroplasty of the fractured vertebra (technique 2). Radiological measurements were taken pre-surgically, post-surgically, at 6 weeks and 3 months, determining the fracture angle, kyphotic deformity, compression and wedging percentage and deformation angle. To assess functional outcome, patients completed the Oswentry Disability Index before surgery and at 3 months.

RESULTS

There were no intraoperative complications of note. In the corpectomy group the mean hospital stay was 9.4 days, with a mean operative time of 250 min, a postoperative haemoglobin loss of 3.3 g/dL and two patients were transfused. In the percutaneous fixation and vertebroplasty group the mean was 5.55 days, surgery time 71 min and loss of 1.6 g/dL haemoglobin. There was one post-surgical haematoma requiring transfusion. None of the patients had to be reoperated during follow-up. Radiological measurements showed adequate correction with both techniques which was maintained over time with minimal loss. In functional outcomes assessed with the Oswentry, patients following technique 1 suffered greater worsening (15%) than those treated with technique 2 (10%).

CONCLUSIONS

In OWF classified as OF4, percutaneous fixation associated with vertebroplasty could be an alternative to corpectomy in older patients with comorbidities, in whom functional recovery is more important than radiological correction. The use of MIS surgery together with improvements in the prevention and treatment of osteoporosis may improve clinical outcomes in the treatment of this type of fracture.

摘要

引言与目的

骨质疏松性椎体骨折(OVF)的发病率正在上升。其诊断和治疗的重要性在于其发生频率以及给患者带来的发病率。德国骨科学与创伤外科学会(DGOU)提出的OVF分类建议对分类为OF4的椎体骨折进行手术治疗。由于椎体结构的显著丧失,这些骨折中的大多数需要前路支撑作为后路固定的辅助手段。在老年患者中,微创手术(MIS)因其对组织的侵袭性较小和全身影响较小而使其能够接受治疗。我们展示了我院脊柱科采用微创技术治疗OF4椎体骨折的结果。

材料与方法

对我院中心治疗的21例胸腰段骨质疏松性OF4骨折患者进行回顾性研究。排除6例行开放性后外侧融合术或单纯椎体成形术的患者。该系列包括15例(13例女性和2例男性),平均年龄72.2岁,通过计算机断层扫描和磁共振成像进行研究。收集临床和分析数据以确定最合适的手术技术。6例采用经胸膜后/腹膜后MIS入路进行部分椎体切除并植入可扩张椎体替代物加长节段后路经皮固定(技术1)。其余9例采用长节段后路经皮固定+骨折椎体椎体成形术(技术2)。术前、术后、6周和3个月进行影像学测量,确定骨折角度、后凸畸形、压缩和楔形变百分比以及变形角度。为评估功能结果,患者在手术前和3个月时完成Oswentry功能障碍指数。

结果

术中无显著并发症。椎体切除组的平均住院时间为9.4天,平均手术时间为250分钟,术后血红蛋白损失3.3 g/dL,2例患者接受输血。经皮固定和椎体成形术组的平均值分别为5.55天、手术时间71分钟和血红蛋白损失1.6 g/dL。有1例术后血肿需要输血。随访期间无患者需要再次手术。影像学测量显示两种技术均有充分的矫正,且随着时间推移保持良好,丢失极少。在用Oswentry评估的功能结果中,采用技术1的患者恶化程度(15%)高于采用技术2的患者(10%)。

结论

在分类为OF4的OWF中,对于患有合并症的老年患者,经皮固定联合椎体成形术可能是椎体切除术的一种替代方法,在这些患者中功能恢复比影像学矫正更重要。MIS手术的应用以及骨质疏松症预防和治疗的改进可能会改善这类骨折治疗的临床结果。

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