General Director's Office.
Biochemistry Department. Centro Médico para Atención Fetal Especializada, Mexico City, Mexico.
Gac Med Mex. 2022;158(1):48-54. doi: 10.24875/GMM.M22000640.
Population-specific reference ranges for uterine artery (UtA) mean pulsatility index (PI) throughout pregnancy have been shown to be of value in antenatal care.
To construct reference values for UtA mean PI throughout pregnancy, customized by maternal characteristics, transvaginal measurement and blood pressure in a Mexican population.
Cross-sectional study in 2286 normal singleton pregnancies in Mexico City. Blood pressure and UtA mean PI were measured using standardized methodology. Reference ranges by gestation were constructed. The effects of independent variables were tested by multiple linear regression.
UtA mean PI median value between 11 and 41 weeks decreased from 1.714 to 0.523. The 95 percentile decreased from 2.600 to 0.653. Previous parity without preeclampsia had the main effect on UtA mean PI. Mean blood pressure had an effect on UtA mean PI by interaction with parity. Previous preeclampsia had an effect on UtA mean PI by interaction with maternal characteristics. A correction factor was obtained for transvaginal measurement.
UtA mean PI usually decreases according to placentation and maternal adaptation to pregnancy. The effects of parity on blood pressure and UtA mean PI might reflect cardiovascular remodeling after gestation.
人群特异性子宫动脉（UtA）平均搏动指数（PI）参考范围在产前保健中具有重要价值。
在墨西哥人群中，构建基于母体特征、经阴道测量和血压的整个孕期 UtA 平均 PI 的参考值。
在墨西哥城进行了一项 2286 例正常单胎妊娠的横断面研究。使用标准化方法测量血压和 UtA 平均 PI。构建随妊娠变化的参考范围。通过多元线性回归测试独立变量的影响。
11-41 周 UtA 平均 PI 的中位数从 1.714 降至 0.523。95%的 PI 从 2.600 降至 0.653。无子痫前期的既往产次是 UtA 平均 PI 的主要影响因素。平均血压通过与产次的相互作用对 UtA 平均 PI 有影响。既往子痫前期通过与母体特征的相互作用对 UtA 平均 PI 有影响。获得了经阴道测量的校正因子。
UtA 平均 PI 通常随胎盘形成和母体对妊娠的适应而降低。产次对血压和 UtA 平均 PI 的影响可能反映了妊娠后心血管重塑。
