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右肝三叶切除术联合全尾状叶切除术非接触技术治疗进展期肝门部胆管癌:1例手术病例报告(附视频)

Right hepatic trisectionectomy combined total caudate lobectomy with non-touch technique for advanced hilar cholangiocarcinoma: A surgical case report (with video).

作者信息

Nguyen Thanh Khiem, Nguyen Ham Hoi, Luong Tuan Hiep, Le Van Khang, Dang Kim Khue, Le Van Duy

机构信息

Department of Gastrointestinal and Hepato-pancreato-biliary surgery, Bach Mai Hospital, Hanoi, Viet Nam.

Department of Surgery, Hanoi Medical University, Viet Nam.

出版信息

Int J Surg Case Rep. 2022 May;94:106987. doi: 10.1016/j.ijscr.2022.106987. Epub 2022 Mar 29.

Abstract

BACKGROUND

Extended resection such as right trisegmentectomy combined with total caudate lobectomy with non-touch technique for advanced hilar cholangiocarcinoma (CCA) is still challenging for all Hepato-pancreato-biliary surgeons.

PRESENTATION

A 45-year-old female with advanced hilar CCA involved the right intrahepatic bile ducts in continuity with the left medial sectional bile duct without PV invasion had undergone right trisegmentectomy combined with total caudate lobectomy with non-touch technique. Dissection of the hepatic peduncle by Lorta-Jacob Procedure, ligation, and resection of the right hepatic artery (RHA) and the right portal vein (PV), before that determine whether portal bifurcation's tumor infiltration or not. Mobilization of the right liver lobe, ligate all the short hepatic veins from the caudal to cranial direction, as well as the right hepatic vein (RHV) and the middle hepatic vein (MHV). Complete caudate lobectomy with right-left approach. Determine hepatic parenchyma cut, left cholangiostomy to the division of the subsegments 2,3, stitch formation of the subsegments 2,3 bile duct. Determine negative upper section of the biliary tract. The operative time was 432 min, and the blood loss was 750 ml. Postoperative recovery was uneventful without any major complications but developed intra-abdominal abscess that required percutaneous drainage.

DISCUSSION

Extended resection procedures such as extend right/left trisectionectomy, hepato-pancreaticoduodenectomy (HPD) and/or combined vascular resection are only curative treatment for advanced hilar CCA. There hadn't been any reported cases describing step-by-step right trisegmentectomy combined with total caudate lobectomy with non-touch technique with clear illustrations and videos yet.

CONCLUSION

Careful preparation with preoperative biliary drainage as well as precise evaluation of the functional capacity of the future liver remnant, as well as meticulous experience of surgeons in hepatic anatomy and non-touch resection technique are key points for success in extended resection for advanced hilar CCA.

摘要

背景

对于所有肝胰胆外科医生而言,扩大切除术,如右三叶切除术联合全尾状叶切除术并采用非接触技术治疗进展期肝门部胆管癌(CCA)仍然具有挑战性。

病例介绍

一名45岁女性,患有进展期肝门部CCA,累及右肝内胆管并与左内侧段胆管连续,无门静脉侵犯,接受了右三叶切除术联合全尾状叶切除术并采用非接触技术。通过洛塔 - 雅各布手术步骤解剖肝蒂,结扎并切除右肝动脉(RHA)和右门静脉(PV),在此之前确定门静脉分叉处是否有肿瘤浸润。游离右肝叶,从尾侧向头侧方向结扎所有肝短静脉,以及右肝静脉(RHV)和中肝静脉(MHV)。采用左右联合入路完成全尾状叶切除术。确定肝实质切割线,在2、3亚段划分处进行左肝管造口术,缝合形成2、3亚段胆管。确定胆道上段切缘阴性。手术时间为432分钟,失血750毫升。术后恢复顺利,无任何重大并发症,但出现了腹腔内脓肿,需要经皮引流。

讨论

扩大切除术,如扩大右/左三叶切除术、肝胰十二指肠切除术(HPD)和/或联合血管切除术,是进展期肝门部CCA的唯一治愈性治疗方法。尚未有任何报道病例详细描述采用非接触技术的逐步右三叶切除术联合全尾状叶切除术,并配有清晰的插图和视频。

结论

术前仔细准备胆道引流,精确评估未来肝余叶的功能能力,以及外科医生在肝脏解剖和非接触切除技术方面的细致经验,是进展期肝门部CCA扩大切除术成功的关键要点。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b44/9006332/350023a59562/gr1.jpg

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