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Covid-19 对中枢神经系统和精神后遗症的潜在影响。

The potential impact of Covid-19 on CNS and psychiatric sequels.

机构信息

Department of Medical Genetics, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.

Department of Biology, Faculty of Science, Shahid Bahonar University of Kerman, Kerman, Iran.

出版信息

Asian J Psychiatr. 2022 Jun;72:103097. doi: 10.1016/j.ajp.2022.103097. Epub 2022 Apr 5.

Abstract

Due to its high prevalence and fatality, the current Severe Acute Respiratory Syndrome-coronavirus-2 (SARS-CoV-2) virus, which first emerged in China in 2019, quickly spread around the world and immediately became a serious global health concern. Although respiratory issues were initially the most prominent symptom of coronavirus disease 2019 (COVID-19), it became obvious rapidly that COVID-19, like many other coronavirus family members, could affect the central nervous system (CNS). During the pandemic, CNS involvement expressed itself in a variety of forms, including insomnia, anosmia, headaches, encephalopathies, encephalitis, cerebrovascular accidents, cognitive and memory impairment, and increased psychiatric disorders. Almost everyone who has been infected has at least one of these neurological symptoms, demonstrating that the virus has a high ability to impact the CNS. As the coronavirus pandemic passes its second year, the manifestations it can cause in the long run, such as its psychological sequels, have not yet been thoroughly studied. Given the high importance of this issue in today's society and due to the lack of reliable knowledge about the COVID-19 landscape on psychiatric disorders, we intend to investigate coronavirus's possible effect on mental illnesses based on available literature. Because the majority of the psychological effects of the coronavirus can continue for a long period after the pandemic ends, our research can give insight into potential psychiatric sequels associated with COVID-19.

摘要

由于其高发病率和死亡率,当前的严重急性呼吸系统综合征冠状病毒 2 型(SARS-CoV-2)病毒于 2019 年首次在中国出现,迅速在全球范围内传播,并立即成为严重的全球健康问题。尽管呼吸道问题最初是 2019 年冠状病毒病(COVID-19)最突出的症状,但很快就明显发现,COVID-19 与许多其他冠状病毒家族成员一样,可能会影响中枢神经系统(CNS)。在大流行期间,CNS 受累以多种形式表现出来,包括失眠、嗅觉丧失、头痛、脑病、脑炎、脑血管意外、认知和记忆障碍以及精神障碍增加。几乎所有感染过的人都至少有一种这些神经系统症状,这表明该病毒具有高度影响 CNS 的能力。随着冠状病毒大流行进入第二年,其在长期内可能引起的表现,例如其心理后遗症,尚未得到彻底研究。鉴于这一问题在当今社会的重要性以及由于对 COVID-19 景观在精神疾病方面缺乏可靠的知识,我们打算根据现有文献研究冠状病毒对精神疾病的可能影响。由于冠状病毒的大多数心理影响可能在大流行结束后持续很长时间,我们的研究可以深入了解与 COVID-19 相关的潜在精神疾病后遗症。

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