• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Covid-19 对中枢神经系统和精神后遗症的潜在影响。

The potential impact of Covid-19 on CNS and psychiatric sequels.

机构信息

Department of Medical Genetics, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.

Department of Biology, Faculty of Science, Shahid Bahonar University of Kerman, Kerman, Iran.

出版信息

Asian J Psychiatr. 2022 Jun;72:103097. doi: 10.1016/j.ajp.2022.103097. Epub 2022 Apr 5.

DOI:10.1016/j.ajp.2022.103097
PMID:35405524
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8982477/
Abstract

Due to its high prevalence and fatality, the current Severe Acute Respiratory Syndrome-coronavirus-2 (SARS-CoV-2) virus, which first emerged in China in 2019, quickly spread around the world and immediately became a serious global health concern. Although respiratory issues were initially the most prominent symptom of coronavirus disease 2019 (COVID-19), it became obvious rapidly that COVID-19, like many other coronavirus family members, could affect the central nervous system (CNS). During the pandemic, CNS involvement expressed itself in a variety of forms, including insomnia, anosmia, headaches, encephalopathies, encephalitis, cerebrovascular accidents, cognitive and memory impairment, and increased psychiatric disorders. Almost everyone who has been infected has at least one of these neurological symptoms, demonstrating that the virus has a high ability to impact the CNS. As the coronavirus pandemic passes its second year, the manifestations it can cause in the long run, such as its psychological sequels, have not yet been thoroughly studied. Given the high importance of this issue in today's society and due to the lack of reliable knowledge about the COVID-19 landscape on psychiatric disorders, we intend to investigate coronavirus's possible effect on mental illnesses based on available literature. Because the majority of the psychological effects of the coronavirus can continue for a long period after the pandemic ends, our research can give insight into potential psychiatric sequels associated with COVID-19.

摘要

由于其高发病率和死亡率,当前的严重急性呼吸系统综合征冠状病毒 2 型(SARS-CoV-2)病毒于 2019 年首次在中国出现,迅速在全球范围内传播,并立即成为严重的全球健康问题。尽管呼吸道问题最初是 2019 年冠状病毒病(COVID-19)最突出的症状,但很快就明显发现,COVID-19 与许多其他冠状病毒家族成员一样,可能会影响中枢神经系统(CNS)。在大流行期间,CNS 受累以多种形式表现出来,包括失眠、嗅觉丧失、头痛、脑病、脑炎、脑血管意外、认知和记忆障碍以及精神障碍增加。几乎所有感染过的人都至少有一种这些神经系统症状,这表明该病毒具有高度影响 CNS 的能力。随着冠状病毒大流行进入第二年,其在长期内可能引起的表现,例如其心理后遗症,尚未得到彻底研究。鉴于这一问题在当今社会的重要性以及由于对 COVID-19 景观在精神疾病方面缺乏可靠的知识,我们打算根据现有文献研究冠状病毒对精神疾病的可能影响。由于冠状病毒的大多数心理影响可能在大流行结束后持续很长时间,我们的研究可以深入了解与 COVID-19 相关的潜在精神疾病后遗症。

相似文献

1
The potential impact of Covid-19 on CNS and psychiatric sequels.Covid-19 对中枢神经系统和精神后遗症的潜在影响。
Asian J Psychiatr. 2022 Jun;72:103097. doi: 10.1016/j.ajp.2022.103097. Epub 2022 Apr 5.
2
Neurological manifestations of SARS-CoV-2: complexity, mechanism and associated disorders.SARS-CoV-2 引发的神经系统表现:复杂性、机制与相关紊乱。
Eur J Med Res. 2023 Aug 30;28(1):307. doi: 10.1186/s40001-023-01293-2.
3
Psychiatric and neuropsychiatric presentations associated with severe coronavirus infections: a systematic review and meta-analysis with comparison to the COVID-19 pandemic.与严重冠状病毒感染相关的精神和神经精神症状表现:一项系统综述和荟萃分析,并与新冠疫情进行比较
Lancet Psychiatry. 2020 Jul;7(7):611-627. doi: 10.1016/S2215-0366(20)30203-0. Epub 2020 May 18.
4
Neurological manifestations associated with SARS-CoV-2 and other coronaviruses: A narrative review for clinicians.与严重急性呼吸综合征冠状病毒2型及其他冠状病毒相关的神经学表现:给临床医生的一篇叙述性综述
Rev Neurol (Paris). 2021 Jan-Feb;177(1-2):51-64. doi: 10.1016/j.neurol.2020.10.001. Epub 2020 Dec 16.
5
A Review of Neurological Involvement in Patients with SARS-CoV-2 Infection.新型冠状病毒感染患者的神经病变综述。
Med Sci Monit. 2021 Jun 19;27:e932962. doi: 10.12659/MSM.932962.
6
Possible mechanism of central nervous system targeting and neurological symptoms of the new-coronavirus (COVID-19): literature review.新型冠状病毒(COVID-19)靶向中枢神经系统的可能机制及神经症状:文献复习。
Eur Rev Med Pharmacol Sci. 2023 Oct;27(19):9420-9428. doi: 10.26355/eurrev_202310_33970.
7
Neuroinvasion, neurotropic, and neuroinflammatory events of SARS-CoV-2: understanding the neurological manifestations in COVID-19 patients.SARS-CoV-2 的神经入侵、嗜神经性和神经炎症事件:了解 COVID-19 患者的神经表现。
Neurol Sci. 2020 Oct;41(10):2657-2669. doi: 10.1007/s10072-020-04575-3. Epub 2020 Jul 28.
8
Neurological symptoms, manifestations, and complications associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease 19 (COVID-19).与严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)和 2019 冠状病毒病(COVID-19)相关的神经症状、表现和并发症。
J Neurol. 2021 Sep;268(9):3059-3071. doi: 10.1007/s00415-021-10406-y. Epub 2021 Jan 23.
9
Neurological toll of COVID-19.新冠病毒对神经系统的影响。
Neurol Sci. 2022 Apr;43(4):2171-2186. doi: 10.1007/s10072-022-05875-6. Epub 2022 Jan 16.
10
Crosstalk between SARS-CoV-2 Infection and Neurological Disorders: A Review.新型冠状病毒2019感染与神经系统疾病之间的相互作用:综述
CNS Neurol Disord Drug Targets. 2023;22(5):643-658. doi: 10.2174/1871527321666220418114009.

引用本文的文献

1
Risk factors for 1-year peripheral neuropathy and F-wave abnormalities after COVID-19: a prospective cohort study.COVID-19后1年周围神经病变和F波异常的危险因素:一项前瞻性队列研究。
Front Neurol. 2025 Jul 8;16:1532046. doi: 10.3389/fneur.2025.1532046. eCollection 2025.
2
First episode of psychiatric and neuropsychiatric disease among patients infected with COVID-19: A scoping review.新型冠状病毒肺炎(COVID-19)感染患者的首发精神和神经精神疾病:一项范围综述
PCN Rep. 2025 Jun 25;4(2):e70146. doi: 10.1002/pcn5.70146. eCollection 2025 Jun.
3
Causal effect of COVID-19 on longitudinal volumetric changes in subcortical structures: A mendelian randomization study.新型冠状病毒肺炎对皮质下结构纵向体积变化的因果效应:一项孟德尔随机化研究。
Heliyon. 2024 Aug 30;10(17):e37193. doi: 10.1016/j.heliyon.2024.e37193. eCollection 2024 Sep 15.
4
SARS-CoV-2 neurovascular invasion supported by Mendelian randomization.基于孟德尔随机化的 SARS-CoV-2 神经血管侵犯。
J Transl Med. 2024 Jan 24;22(1):101. doi: 10.1186/s12967-024-04907-3.
5
Causal associations between COVID-19 and childhood mental disorders.新冠病毒与儿童精神障碍之间的因果关系。
BMC Psychiatry. 2023 Dec 8;23(1):922. doi: 10.1186/s12888-023-05433-0.
6
Causal influences of osteoarthritis on COVID-19: a Mendelian randomization study.骨关节炎对2019冠状病毒病的因果影响:一项孟德尔随机化研究。
Front Med (Lausanne). 2023 Oct 31;10:1287043. doi: 10.3389/fmed.2023.1287043. eCollection 2023.
7
Assessment and Psychometric Properties of the 21-Item Depression Anxiety Stress Scale (DASS-21) among Portuguese Higher Education Students during the COVID-19 Pandemic.21项抑郁焦虑压力量表(DASS-21)在葡萄牙高等教育学生中于新冠疫情期间的评估及心理测量特性
Eur J Investig Health Psychol Educ. 2023 Nov 6;13(11):2546-2560. doi: 10.3390/ejihpe13110177.
8
Addressing psychosomatic issues after lifting the COVID-19 policy in China: A wake-up call.探讨中国解除新冠疫情政策后的身心问题:敲响警钟。
Asian J Psychiatr. 2023 Apr;82:103517. doi: 10.1016/j.ajp.2023.103517. Epub 2023 Feb 11.
9
Long term neuropsychiatric consequences in COVID-19 survivors: Cognitive impairment and inflammatory underpinnings fifteen months after discharge.COVID-19 幸存者的长期神经精神后果:出院后 15 个月的认知障碍和炎症基础。
Asian J Psychiatr. 2023 Feb;80:103409. doi: 10.1016/j.ajp.2022.103409. Epub 2022 Dec 15.
10
Severe COVID-19 increases the risk of schizophrenia.严重的 COVID-19 增加了患精神分裂症的风险。
Psychiatry Res. 2022 Nov;317:114809. doi: 10.1016/j.psychres.2022.114809. Epub 2022 Aug 24.

本文引用的文献

1
Reactive psychoses in the context of the COVID-19 pandemic: Clinical perspectives from a case series.2019冠状病毒病大流行背景下的反应性精神病:来自一系列病例的临床观点
Rev Psiquiatr Salud Ment. 2020 Apr-Jun;13(2):90-94. doi: 10.1016/j.rpsm.2020.04.009. Epub 2020 Apr 27.
2
Social and Biological Parameters Involved in Suicide Ideation During the COVID-19 Pandemic: A Narrative Review.新冠疫情期间与自杀意念相关的社会和生物学参数:一项叙述性综述
Int J Tryptophan Res. 2020 Dec 21;13:1178646920978243. doi: 10.1177/1178646920978243. eCollection 2020.
3
Adjustment disorder, traumatic stress, depression and anxiety in Poland during an early phase of the COVID-19 pandemic.波兰在 COVID-19 大流行早期的调整障碍、创伤后应激、抑郁和焦虑。
Eur J Psychotraumatol. 2021 Jan 26;12(1):1860356. doi: 10.1080/20008198.2020.1860356. eCollection 2021.
4
Tryptophan-Kynurenine Pathway in COVID-19-Dependent Musculoskeletal Pathology: A Minireview.COVID-19 相关肌肉骨骼病理学中的色氨酸-犬尿氨酸途径:简要综述。
Mediators Inflamm. 2021 Oct 5;2021:2911578. doi: 10.1155/2021/2911578. eCollection 2021.
5
First-Episode Psychosis With Delusional Jealousy During SARS-CoV-2 Infection: COVID-19 Secondary Psychosis or a Trigger for a Primary Psychotic Disorder?新型冠状病毒感染期间伴嫉妒妄想的首发精神病:是新冠病毒感染继发的精神病还是原发性精神障碍的诱因?
Prim Care Companion CNS Disord. 2021 Sep 30;23(5):21cr03070. doi: 10.4088/PCC.21cr03070.
6
Symptoms of major depressive disorder during the COVID-19 pandemic: results from a representative sample of the Canadian population.在 COVID-19 大流行期间的重度抑郁症的症状:来自加拿大代表性人群样本的结果。
Health Promot Chronic Dis Prev Can. 2021 Nov 10;41(11):340-358. doi: 10.24095/hpcdp.41.11.04. Epub 2021 Sep 27.
7
Lifting lockdown COVID19 restrictions: What can pharmacists do as the world wakes up?解除新冠疫情封锁限制:随着世界复苏,药剂师能做些什么?
Explor Res Clin Soc Pharm. 2021 Jun;2:100028. doi: 10.1016/j.rcsop.2021.100028. Epub 2021 Jun 12.
8
Prevalence and Correlates of Suicidal Ideation and Deliberate Self-harm in Canadian Adolescents During the Coronavirus Disease 2019 Pandemic.新冠疫情期间加拿大青少年自杀意念和故意自伤的流行率及其相关因素。
Can J Psychiatry. 2022 May;67(5):403-406. doi: 10.1177/07067437211036612. Epub 2021 Aug 11.
9
Prevalence and Correlates of Likely Major Depressive Disorder among the Adult Population in Ghana during the COVID-19 Pandemic.加纳 COVID-19 大流行期间成年人口中可能患有重度抑郁症的流行状况及相关因素。
Int J Environ Res Public Health. 2021 Jul 2;18(13):7106. doi: 10.3390/ijerph18137106.
10
Obstructive sleep apnea is highly prevalent in COVID19 related moderate to severe ARDS survivors: findings of level I polysomnography in a tertiary care hospital.阻塞性睡眠呼吸暂停在 COVID19 相关的中重度 ARDS 幸存者中极为普遍:三级保健医院的 I 级多导睡眠图研究结果。
Sleep Med. 2022 Mar;91:226-230. doi: 10.1016/j.sleep.2021.06.015. Epub 2021 Jun 19.