Laboratory of Comorbidity in Cardiovascular Diseases, FSBSI Research Institute for Complex Issues of Cardiovascular Diseases, Sosnovy Blvd. 6, 650002 Kemerovo, Russia.
Int J Environ Res Public Health. 2022 Apr 4;19(7):4329. doi: 10.3390/ijerph19074329.
The purpose of this work was to study the factors determining the functional state of cardiac surgery patients with a complicated postoperative period upon discharge from the hospital. This observational study included 60 patients who underwent cardiac surgery with a complicated postoperative course and with a prolonged intensive care unit stay of more than 72 h. We assessed handgrip and lower-extremity muscle strength and the six-minute walk test (6MWT) distance 3 days after the surgery and at discharge from the hospital. Some patients (53%) additionally underwent a course of neuromuscular electrostimulation (NMES). Two groups of patients were formed: first (6MWT distance at discharge of more than 300 m) and second groups (6MWT distance of 300 m or less). The patients of the second group had less lower-extremity muscle strength and handgrip strength on the third postoperative day, a longer aortic clamping time and a longer stay in the intensive care unit. Independent predictors of decreased exercise tolerance at discharge were body mass index, foot extensor strength and baseline 6MWT distance in the general group, duration of cardiopulmonary bypass in the NMES group and in the general group, and age in the NMES group. Thus, the muscle status on the third postoperative day was one of the independent factors associated with the 6MWT distance at discharge in the general group, but not in patients who received NMES. It is advisable to use these results in patients with complications after cardiac surgery with the use of NMES rehabilitation.
本研究旨在探讨心脏外科术后复杂患者出院时心功能状态的决定因素。这项观察性研究纳入了 60 例心脏外科术后病程复杂且 ICU 住院时间超过 72 小时的患者。我们在术后 3 天和出院时评估了握力和下肢肌肉力量以及 6 分钟步行试验(6MWT)距离。部分患者(53%)还接受了神经肌肉电刺激(NMES)治疗。将患者分为两组:第一组(出院时 6MWT 距离超过 300m)和第二组(6MWT 距离为 300m 或以下)。第二组患者在术后第 3 天的下肢肌肉力量和握力较小,主动脉夹闭时间较长,ICU 住院时间较长。一般组中,出院时运动耐量降低的独立预测因素为体重指数、足伸肌力量和基线 6MWT 距离,NMES 组和一般组中体外循环持续时间以及 NMES 组中年龄。因此,术后第 3 天的肌肉状态是一般组中与 6MWT 距离相关的独立因素之一,但在接受 NMES 治疗的患者中并非如此。对于接受 NMES 康复治疗的心脏手术后并发症患者,建议使用这些结果。