Manolitsis Ioannis, Tzelves Lazaros, Bellos Themistoklis, Berdempes Marinos, Skolarikos Andreas
Second Department of Urology, National and Kapodistrian University of Athens, Sismanogleio General Hospital, Athens, GRC.
Cureus. 2022 Mar 8;14(3):e22956. doi: 10.7759/cureus.22956. eCollection 2022 Mar.
Testicular cancer is the most common neoplasm in men aged 15-45 years old, with several established risk factors such as cryptorchidism, age, and family history. We report a case of a 44-year-old man with a history of cryptorchidism who presented with lesions in his right testis, a large retroperitoneal mass, and diffuse nodal lesions in his lungs. He underwent radical orchiectomy that showed testicular cancer and was immediately inducted into systemic therapy based on bleomycin, etoposide, and cisplatin. Two weeks later, his monozygotic twin brother, also reporting cryptorchidism at a young age, presented with a painless mass in his left testis. He underwent radical orchiectomy that revealed testicular cancer and received adjuvant chemotherapy. The first patient, after two cycles of chemotherapy, suffered from an episode of massive hematochezia and died while his brother remains relapse-free.
睾丸癌是15至45岁男性中最常见的肿瘤，有几个已确定的风险因素，如隐睾症、年龄和家族史。我们报告一例44岁男性病例，该患者有隐睾症病史，出现右侧睾丸病变、巨大腹膜后肿块及肺部弥漫性淋巴结病变。他接受了根治性睾丸切除术，术后病理显示为睾丸癌，并立即接受基于博来霉素、依托泊苷和顺铂的全身治疗。两周后，他的同卵双胞胎兄弟，同样在年轻时有隐睾症病史，左侧睾丸出现无痛性肿块。他接受了根治性睾丸切除术，术后病理显示为睾丸癌，并接受了辅助化疗。第一名患者在两个周期化疗后，出现大量便血并死亡，而他的兄弟仍无复发。
