Korman D B
Vopr Onkol. 1978;24(7):51-5.
Umder study was the survival rate in 73 patients treated routinely with 5-fluoruracil for recurrences and metastases of gastric cancer. The survival of 33 patients, treated with the clinical effect proved to be reliably higher than that in 40 patients in whom no effect was gained (the time of 50% survival was 7.1 and 2.4 months accordingly). The compared groups of patients did not differ reliably in such prognostic factors as the tumor spread to the onset of chemotherapy and duration of the interval since the primary operation till tumor progression. It is concluded that the longer survival in patients treated with the effect is due to 5-fluoruracil administration.
本研究针对73例因胃癌复发和转移而常规接受5-氟尿嘧啶治疗的患者的生存率进行了研究。33例患者经治疗后临床疗效可靠，其生存率高于40例未取得疗效的患者（50%生存率的时间分别为7.1个月和2.4个月）。在肿瘤扩散至化疗开始的时间以及从初次手术至肿瘤进展的间隔时间等预后因素方面，两组患者之间并无可靠差异。得出的结论是，治疗有效的患者生存期较长是由于使用了5-氟尿嘧啶。
