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癌症的自身免疫性质。

The autoimmune nature of cancer.

作者信息

Prehn R T, Prehn L M

出版信息

Cancer Res. 1987 Feb 15;47(4):927-32.

PMID:3542202
Abstract

Four different kinds of data from the 3-methylcholanthrene-induced sarcoma system of the mouse show that the immune system stimulates oncogenesis; i.e., the presence of a tumor-specific immune reaction is a positive aid to tumor development. It seems proper, therefore, to consider cancer, at least in part, an autoimmune disease.

摘要

来自小鼠3-甲基胆蒽诱导肉瘤系统的四种不同类型的数据表明，免疫系统会刺激肿瘤发生；也就是说，肿瘤特异性免疫反应的存在对肿瘤发展有积极促进作用。因此，似乎有理由认为癌症至少在一定程度上是一种自身免疫性疾病。

相似文献

1
The autoimmune nature of cancer.癌症的自身免疫性质。
Cancer Res. 1987 Feb 15;47(4):927-32.
2
Immunogenic strength of sarcomas induced by methylcholanthrene in millipore filter diffusion chambers.甲基胆蒽在微孔滤膜扩散小室中诱导产生的肉瘤的免疫原性强度。
Cancer Res. 1973 Apr;33(4):750-4.
3
Host and tumor modifications associated with serial heterotransplantation of tumors through immunologically tolerant animals.与肿瘤通过免疫耐受动物进行系列异种移植相关的宿主和肿瘤改变。
Cancer Res. 1970 Jun;30(6):1681-91.
4
Cancer and the immune response.癌症与免疫反应。
Proc Inst Med Chic. 1973 Jul-Aug;29(10):339-45.
5
Curative intravenous adoptive immunotherapy of Meth A murine sarcoma. A histologic and immunohistochemical assessment.甲种小鼠肉瘤的静脉内治疗性过继免疫疗法。组织学和免疫组织化学评估。
Lab Invest. 1985 Mar;52(3):304-13.
6
Antigenicity of cells derived from mouse prostate cells after malignant transformation in vitro by carcinogenic hydrocarbons.致癌碳氢化合物体外恶性转化后源自小鼠前列腺细胞的细胞的抗原性。
Cancer Res. 1970 Jun;30(6):1593-7.
7
Stimulation of transplanted 3-methylcholanthrene-induced sarcomas in mice by specific immune ahd by normal serum.通过特异性免疫和正常血清刺激小鼠移植的3-甲基胆蒽诱导肉瘤。
Int J Cancer. 1976 Jun 15;17(6):755-64. doi: 10.1002/ijc.2910170611.
8
Study of the immunogenic strength of sarcomas induced in diffusion chambers.扩散小室中诱导产生的肉瘤免疫原性强度的研究。
Schweiz Med Wochenschr. 1972 Aug 19;102(33):1151-2.
9
Syngeneic monoclonal antibodies to a methylcholanthrene-induced mouse sarcoma.针对甲基胆蒽诱导的小鼠肉瘤的同基因单克隆抗体。
Transplant Proc. 1980 Mar;12(1):95-8.
10
[Serological determination of specific surface antigens of cells from sarcomas induced by methylcholanthrene].[甲基胆蒽诱导的肉瘤细胞特异性表面抗原的血清学测定]
Tsitologiia. 1970 May;12(5):666-74.

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1
Logistic regression prediction model identify type 2 diabetes mellitus as a prognostic factor for human papillomavirus-16 associated head and neck squamous cell carcinoma.逻辑回归预测模型将 2 型糖尿病确定为人乳头瘤病毒-16 相关头颈部鳞状细胞癌的预后因素。
PLoS One. 2019 May 16;14(5):e0217000. doi: 10.1371/journal.pone.0217000. eCollection 2019.
2
A new kink in an old theory of carcinogenesis.致癌作用旧理论中的一个新转折。
Theor Biol Med Model. 2013 Feb 18;10:12. doi: 10.1186/1742-4682-10-12.
3
Evidence for a human-specific mechanism for diet and antibody-mediated inflammation in carcinoma progression.
饮食和抗体介导的炎症在癌症进展中的人类特异性机制的证据。
Proc Natl Acad Sci U S A. 2008 Dec 2;105(48):18936-41. doi: 10.1073/pnas.0803943105. Epub 2008 Nov 18.
4
Diversity in specificity, abundance, and composition of anti-Neu5Gc antibodies in normal humans: potential implications for disease.正常人体内抗Neu5Gc抗体在特异性、丰度和组成上的多样性：对疾病的潜在影响。
Glycobiology. 2008 Oct;18(10):818-30. doi: 10.1093/glycob/cwn072. Epub 2008 Jul 31.
5
Does the immune reaction cause malignant transformation by disrupting cell-to-cell or cell-to-matrix communications?免疫反应是否通过破坏细胞间或细胞与基质间的通讯而导致恶性转化？
Theor Biol Med Model. 2007 May 4;4:16. doi: 10.1186/1742-4682-4-16.
6
On the nature of cancer and why anticancer vaccines don't work.论癌症的本质及抗癌疫苗为何无效。
Cancer Cell Int. 2005 Aug 1;5(1):25. doi: 10.1186/1475-2867-5-25.
7
Allergic contact sensitizing chemicals as environmental carcinogens.作为环境致癌物的变应性接触致敏化学物质。
Environ Health Perspect. 1997 Sep;105(9):940-8. doi: 10.1289/ehp.97105940.
8
Tumor immunogenicity: how far can it be pushed?肿瘤免疫原性：其可被提升到何种程度？
Proc Natl Acad Sci U S A. 1993 May 15;90(10):4332-3. doi: 10.1073/pnas.90.10.4332.
9
Anti-inflammation induced by counter-irritation or by treatment with non-steroidal agents inhibits the growth of a tumour of non-detected immunogenicity.通过反刺激或使用非甾体类药物诱导的抗炎作用可抑制未检测到免疫原性的肿瘤生长。
Br J Cancer. 1989 Nov;60(5):734-8. doi: 10.1038/bjc.1989.349.
10
Mitogenic regulation of normal and malignant breast epithelium.正常和恶性乳腺上皮的促有丝分裂调控。
Yale J Biol Med. 1989 Sep-Oct;62(5):459-80.