Kim Hyun Soo, Pyo Hong Jin, Fava Maurizio, Mischoulon David, Park Mi Jin, Jeon Hong Jin
Department of Psychiatry, Depression Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.
Depression Clinical and Research Program, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
Front Psychiatry. 2022 Mar 25;13:792734. doi: 10.3389/fpsyt.2022.792734. eCollection 2022.
There is an association between early life traumas and the development of depression in adults. Few studies have used nationwide population-based samples to investigate whether the type of early life trauma differentially influences the risk of developing depression.
Major depressive disorder and early life trauma were assessed using the Korean version of the Composite International Diagnostic Interview (K-CIDI) for DSM-IV psychiatric disorder and a questionnaire for early life trauma in the Korean Epidemiological Catchment Area Study in 2016. A total of 4,652 participants were included in the final analysis. This study evaluated the effect of the type and frequency of reported early life trauma on the risk of developing MDD and the association between reported early life trauma and differential symptoms of MDD.
Individuals with reported early life trauma had a 3.7-fold increased risk of MDD. The risk of MDD was associated with bullying trauma (odds ratio (OR) = 1.847, = 0.005) after adjusting for age, gender, marriage, job, and education years. The risk of MDD was increased as the types of reported early life traumas increased.
Bullying trauma during early life represents a risk factor for MDD, especially in individuals exposed to multiple traumas in early life.
早年创伤与成年人抑郁症的发生之间存在关联。很少有研究使用全国性的基于人群的样本,来调查早年创伤的类型是否会对患抑郁症的风险产生不同影响。
在2016年韩国流行病学流域研究中,使用针对DSM-IV精神障碍的韩国版综合国际诊断访谈(K-CIDI)和一份关于早年创伤的问卷,对重度抑郁症和早年创伤进行评估。最终分析共纳入4652名参与者。本研究评估了报告的早年创伤的类型和频率对患重度抑郁症风险的影响,以及报告的早年创伤与重度抑郁症不同症状之间的关联。
报告有早年创伤的个体患重度抑郁症的风险增加了3.7倍。在调整年龄、性别、婚姻状况、工作和受教育年限后,重度抑郁症的风险与欺凌创伤相关(优势比(OR)=1.847,=0.005)。随着报告的早年创伤类型增加,患重度抑郁症的风险也增加。
早年的欺凌创伤是重度抑郁症的一个风险因素,尤其是在早年经历过多种创伤的个体中。