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高产率一锅法合成具有在宽范围内可调且明确的穿线比的聚轮烷。

High-yield one-pot synthesis of polyrotaxanes with tunable well-defined threading ratios over a wide range.

作者信息

Noritomi Takako, Jiang Lan, Yokoyama Hideaki, Mayumi Koichi, Ito Kohzo

机构信息

Material Innovation Research Center (MIRC) and Department of Advanced Materials Science, Graduate School of Frontier Sciences, The University of Tokyo 5-1-5 Kashiwanoha Kashiwa Chiba 277-8561 Japan

The Institute for Solid State Physics, The University of Tokyo 5-1-5 Kashiwanoha Kashiwa Chiba 277-8581 Japan

出版信息

RSC Adv. 2022 Jan 30;12(7):3796-3800. doi: 10.1039/d1ra09475k. eCollection 2022 Jan 28.

DOI:10.1039/d1ra09475k
PMID:35425463
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8981155/
Abstract

In this work, we report a high-yield one-pot synthesis of polyrotaxane (PR), composed of (2-hydroxypropyl)-α-cyclodextrin (hpCD) and polyethylene glycol (PEG), with well-defined hpCD threading ratios controllable across a wide range from 0.64% to 10%. In hpCD/PEG aqueous solutions, hpCDs are well dispersed and threaded spontaneously into hpCDs to form a pseudo-PR (pPR) structure. The homogeneous dispersion of hpCDs results in a well-defined threading ratio of hpCDs on PEG, which is suggested by the fact that the dispersity of the molecular weight distribution of PR is almost the same as that of pure PEG. The well-defined hpCD threading ratio of the PRs can be controlled over a wide range by tuning the hpCD concentration in the pPR solutions.

摘要

在本工作中，我们报道了一种由（2-羟丙基）-α-环糊精（hpCD）和聚乙二醇（PEG）组成的聚轮烷（PR）的高产率一锅法合成方法，其具有明确的hpCD穿线比率，可在0.64%至10%的宽范围内控制。在hpCD/PEG水溶液中，hpCDs分散良好，并自发地穿入hpCDs中形成假聚轮烷（pPR）结构。hpCDs的均匀分散导致hpCDs在PEG上具有明确的穿线比率，这由PR的分子量分布分散度与纯PEG几乎相同这一事实表明。通过调节pPR溶液中hpCD的浓度，可以在很宽的范围内控制PRs明确的hpCD穿线比率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4eee/8981155/5ada98c1f48a/d1ra09475k-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4eee/8981155/e2bdd9f5756a/d1ra09475k-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4eee/8981155/f10b2a16bdd3/d1ra09475k-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4eee/8981155/ba8abf4399d3/d1ra09475k-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4eee/8981155/5ada98c1f48a/d1ra09475k-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4eee/8981155/e2bdd9f5756a/d1ra09475k-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4eee/8981155/f10b2a16bdd3/d1ra09475k-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4eee/8981155/ba8abf4399d3/d1ra09475k-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4eee/8981155/5ada98c1f48a/d1ra09475k-f4.jpg

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本文引用的文献

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