Wang Wenxin, Lv Wei, Yang Jianquan
Department of Neurosurgery, Renmin Hospital, Hubei University of Medicine, Shiyan, China.
Department of Neurosurgery, Wuhan Asia General Hospital, Wuhan, China.
Front Surg. 2022 Mar 29;9:837008. doi: 10.3389/fsurg.2022.837008. eCollection 2022.
The study aimed to explore the efficacy and safety of modified transfrontal puncture drainage in patients with hypertensive basal ganglia hemorrhage.
The study enrolled 102 patients with hypertensive basal ganglia hemorrhage who received treatment at our hospital between April 2020 and June 2020. They were divided into a control group (51 cases, burr hole evacuation of intracranial hematoma) and a study group (51 cases, modified transfrontal puncture drainage) using the random number table method. The operative time, hematoma evacuation rate, time to recovery of consciousness, postoperative Glasgow coma scales (GOS), and the length of hospital stay were compared between the two groups. The postoperative recovery of neurological function in the two groups was observed, and activities of daily living at 3 months postoperatively in the two groups were statistically analyzed. The postoperative complications and recurrent bleeding, as well as prognosis in the two groups, were recorded.
The operative time, hematoma evacuation rate, time to recovery of consciousness, postoperative GOS scores, time to extubation, and the length of hospital stay of the two groups were compared postoperatively, and the difference was statistically significant ( < 0.05). The preoperative neurological function of the two groups was compared, and the difference was statistically insignificant ( > 0.05). The postoperative neurological function of the study group was lower than that of the control group, and the difference was statistically significant ( < 0.05). The postoperative incidence of stress ulcer, renal failure, and recurrent bleeding in the two groups was compared, and the difference was statistically insignificant ( > 0.05). The rate of pulmonary infections and gastrointestinal bleeding in the study group was lower than that of the control group, and the difference was statistically significant ( < 0.05). The mortality rate of the study group was 1.96% (1/51) and that of the control group was 3.92% (2/51), and the difference was statistically insignificant ( > 0.05). The activities of daily living in the two groups were compared and the difference was statistically insignificant ( > 0.05).
Modified transfrontal puncture drainage can effectively treat hypertensive basal ganglia hemorrhage patients and has relatively good safety.
本研究旨在探讨改良经额穿刺引流术治疗高血压基底节区脑出血患者的疗效及安全性。
选取2020年4月至2020年6月在我院接受治疗的102例高血压基底节区脑出血患者,采用随机数字表法将其分为对照组(51例,采用颅骨钻孔血肿清除术)和研究组(51例,采用改良经额穿刺引流术)。比较两组患者的手术时间、血肿清除率、意识恢复时间、术后格拉斯哥昏迷量表(GOS)评分及住院时间。观察两组患者术后神经功能恢复情况,并对两组患者术后3个月的日常生活活动能力进行统计学分析。记录两组患者术后并发症、再出血情况及预后。
术后比较两组患者的手术时间、血肿清除率、意识恢复时间、术后GOS评分、拔管时间及住院时间,差异有统计学意义(<0.05)。比较两组患者术前神经功能,差异无统计学意义(>0.05)。研究组患者术后神经功能低于对照组,差异有统计学意义(<0.05)。比较两组患者术后应激性溃疡、肾衰竭及再出血发生率,差异无统计学意义(>0.05)。研究组患者肺部感染及消化道出血发生率低于对照组,差异有统计学意义(<0.05)。研究组患者死亡率为1.96%(1/51),对照组患者死亡率为3.92%(2/51),差异无统计学意义(>0.05)。比较两组患者日常生活活动能力,差异无统计学意义(>0.05)。
改良经额穿刺引流术可有效治疗高血压基底节区脑出血患者,且安全性相对较好。