Department of Surgery, UMass Chan Medical School, Worcester, Massachusetts, USA.
Department of Surgery, St. Mary's Hospital, Waterbury, Connecticut, USA.
Clin Obes. 2022 Aug;12(4):e12526. doi: 10.1111/cob.12526. Epub 2022 Apr 15.
The morbidity and mortality of deep vein thrombosis (DVT) remain a significant burden for the healthcare system. The aim of this analysis was to examine the association of upper extremity central venous catheter (UECVC) and venous thromboembolism (UEVTE) with increasing body mass index (BMI) in a large database study and to further examine disposition. Inpatient data from the National Inpatient Sample from 2017 to 2019 were used to investigate the effect of obesity on patients diagnosed with DVT of the upper extremity or pulmonary embolism (PE) who had upper extremity venous central line placement. There was a total of 1690 cases of UEVTE and 3202 cases of PE within the sample. There was an increasing odds of UEVTE in the patients with UECVCs with increasing BMI. Patients with a BMI of 30-39, 40-49 and > 50 kg/m were significantly different than those with BMI of <19 and 20-29 kg/m in the UECVC group for UEVTE. This study demonstrated increased odds of UEVTE for patients with increased BMI. Practitioners should assume a greater risk for UEVTE and PE in patients with increased BMI when considering CVCs.
深静脉血栓形成（DVT）的发病率和死亡率仍然是医疗系统的一个重大负担。本分析的目的是在一个大型数据库研究中检查上肢中心静脉导管（UECVC）和静脉血栓栓塞（UEVTE）与体重指数（BMI）增加的相关性，并进一步检查处置情况。使用 2017 年至 2019 年全国住院患者样本中的住院数据，调查肥胖对诊断为上肢 DVT 或肺栓塞（PE）且上肢静脉中心置管的患者的影响。在样本中，共有 1690 例 UEVTE 和 3202 例 PE。随着 BMI 的增加，患有 UECVC 的患者发生 UEVTE 的几率增加。与 BMI<19 和 20-29 kg/m 的患者相比，BMI 为 30-39、40-49 和>50 kg/m 的患者在 UECVC 组中发生 UEVTE 的几率明显更高。这项研究表明，BMI 增加的患者发生 UEVTE 的几率增加。在考虑 CVC 时，从业者应假设 BMI 增加的患者发生 UEVTE 和 PE 的风险更高。
