Lahey Hospital and Medical Center, Burlington, Massachusetts, USA.
University of Michigan, Ann Arbor, Michigan, USA.
Can J Urol. 2022 Apr;29(2):11080-11086.
To assess the association between postoperative discharge day after minimally invasive partial nephrectomy with 30-day readmission rates, and specifically compare postoperative day 1 to postoperative day 2 discharge. We hypothesized that discharge on earlier postoperative days would be associated with higher rates of readmission after partial nephrectomy.
The National Cancer Database was queried for patients undergoing minimally invasive partial nephrectomy for non-metastatic disease without chemo or radiation therapy from 2010-2014. Readmission rates were compared between postoperative discharge days. Multivariable logistic regression was used to analyze variables associated with 30-day readmission.
A total of 19,300 patients undergoing minimally invasive partial nephrectomy were included, comprising patients discharged on postoperative day 0 (POD0) (n = 601, 3%), POD1 (n = 2,999, 16%), POD2 (n = 6,866, 36%), POD3 (n = 4,568, 24%), POD4 (n = 2,068, 11%), and POD5 or later (n = 2,198, 11%). Rates of 30-day readmission were similar between POD0, POD1 and POD2 discharges (1.8%, 1.9%, 2.2%, respectively), but were higher for discharges on POD3 or later (POD3 3.0%, POD4 4.9%, POD5 or greater 5.5%). On multivariable analysis, odds of 30-day readmission were similar between POD0 (OR 0.83 [95%CI 0.45-1.55], p = 0.56) and POD1 (OR 0.84 [95%CI 0.62-1.15], p = 0.28) compared to discharge on POD2.
Patients discharged on POD2 are not readmitted any less frequently than patients discharged on POD0 or POD1. Implementing protocols with POD1 as the default discharge day after partial nephrectomy should be considered. Future studies designing and evaluating safe and acceptable implementation strategies for these protocols are necessary.
评估微创部分肾切除术(minimally invasive partial nephrectomy)后第 30 天再入院率与术后出院日之间的关系,特别是比较术后第 1 天和第 2 天出院的情况。我们假设更早的术后出院日与部分肾切除术后再入院率较高相关。
2010 年至 2014 年间,我们对国家癌症数据库(National Cancer Database)中接受微创部分肾切除术治疗非转移性疾病且未接受化疗或放疗的患者进行了检索。比较了不同术后出院日的再入院率。采用多变量逻辑回归分析与 30 天再入院相关的变量。
共纳入 19300 例行微创部分肾切除术的患者,包括术后第 0 天(POD0)出院的患者(n=601,3%)、术后第 1 天(POD1)出院的患者(n=2999,16%)、术后第 2 天(POD2)出院的患者(n=6866,36%)、术后第 3 天(POD3)出院的患者(n=4568,24%)、术后第 4 天(POD4)出院的患者(n=2068,11%)和术后第 5 天或更晚出院的患者(n=2198,11%)。POD0、POD1 和 POD2 出院患者的 30 天再入院率相似(分别为 1.8%、1.9%和 2.2%),但 POD3 或更晚出院的患者再入院率更高(POD3 为 3.0%,POD4 为 4.9%,POD5 或更晚为 5.5%)。多变量分析显示,与 POD2 出院相比,POD0(OR 0.83[95%CI 0.45-1.55],p=0.56)和 POD1(OR 0.84[95%CI 0.62-1.15],p=0.28)出院患者的 30 天再入院率相似。
与 POD2 出院相比,POD0 或 POD1 出院患者的再入院频率并没有降低。应考虑将 POD1 作为部分肾切除术后默认的出院日。有必要设计并评估这些方案的安全且可接受的实施策略。