Lecturer, Department of Pediatric Dentistry, Faculty of Dentistry, Erciyes University, Kayseri, Turkey.
Associate Professor, Department of Pediatric Dentistry, Faculty of Dentistry, Erciyes University, Kayseri, Turkey.
J Oral Maxillofac Surg. 2022 Jul;80(7):1223-1237. doi: 10.1016/j.joms.2022.03.013. Epub 2022 Mar 22.
Odontogenic cysts can cause changes in bone structure. The purpose of this study is to evaluate the change in bone healing before and after decompression of nonsyndromic odontogenic cysts in children.
A retrospective cohort study was performed including children diagnosed with nonsyndromic odontogenic cysts between January 2016 and December 2020. Study variables included the measurement times (baseline: T, 1-month postoperative: T, and end treatment: T), measurement regions (middle cyst and control area), maxilla, and mandible. The primary and secondary outcome variables were fractal dimension (FD), treatment time, and cyst volume, respectively. Bone healing was evaluated using the fractal analysis method, the results of which are expressed as the FD. Data were analyzed by Friedman repeated measures analysis of variance by ranks, the Wilcoxon rank, Mann-Whitney U, and Kruskal-Wallis tests, Spearman correlation analysis, and linear regression model.
Twenty-three children (9 girls,14 boys) with a mean age of 9.57 ± 2.02 years were included into the study. A comparison of the measurement regions showed that the middle cyst area (1.279 ± 0.090) had significantly lower FD values than control area before decompression (T; P < .001). Statistically significant differences were observed in FD values at T, T, and T (1.279 ± 0.090, 1.311 ± 0.090, and 1.384 ± 0.075) in the middle cyst area (P <. 001). After decompression, no significant difference was found in FD values between the middle cyst (1.384 ± 0.075) and the control area (1.401 ± 0.050).
Decompression resulted in successful bone healing in children with odontogenic cysts. Conservative treatment methods should be preferred due to the continuation of growth and development in pediatric patients.
牙源性囊肿可引起骨结构改变。本研究旨在评估儿童非综合征性牙源性囊肿减压前后的骨愈合变化。
回顾性队列研究纳入 2016 年 1 月至 2020 年 12 月期间诊断为非综合征性牙源性囊肿的儿童。研究变量包括测量时间（基线：T、术后 1 个月：T、和治疗结束：T）、测量区域（囊肿中部和对照区）、上颌骨和下颌骨。主要和次要结局变量分别为分形维数（FD）、治疗时间和囊肿体积。骨愈合采用分形分析方法评估，结果以 FD 表示。采用 Friedman 重复测量方差分析、Wilcoxon 秩和检验、Mann-Whitney U 检验、Kruskal-Wallis 检验、Spearman 相关分析和线性回归模型对数据进行分析。
本研究纳入了 23 名儿童（9 名女孩，14 名男孩），平均年龄为 9.57±2.02 岁。与减压前相比，囊肿中部（1.279±0.090）的 FD 值明显较低（T；P<.001）。在囊肿中部的 T、T 和 T 时，FD 值存在统计学差异（1.279±0.090、1.311±0.090 和 1.384±0.075）（P<.001）。减压后，囊肿中部（1.384±0.075）与对照区（1.401±0.050）的 FD 值无显著差异。
减压可成功促进儿童牙源性囊肿的骨愈合。由于儿童患者仍处于生长发育阶段，应优先选择保守治疗方法。
