Department of Otolaryngology - Head and Neck Surgery, University of Missouri School of Medicine, 1 Hospital Drive, Columbia, MO 65212, United States of America.
Department of Otolaryngology - Head and Neck Surgery, University of Missouri School of Medicine, 1 Hospital Drive, Columbia, MO 65212, United States of America.
Am J Otolaryngol. 2022 May-Jun;43(3):103450. doi: 10.1016/j.amjoto.2022.103450. Epub 2022 Apr 5.
To report a very rare case of incidentally discovered Medullary Thyroid Carcinoma after total thyroidectomy in a patient with Graves' disease, review available literature, and present readers with management information.
Medullary Thyroid Carcinoma in the setting of Graves' disease is a rare scenario. Only fifteen total cases besides ours has been described in literature, and only six other cases were incidentally discovered.
When Medullary Thyroid Carcinoma is incidentally discovered in the setting of Graves' disease, retroactive workup should begin with postoperative calcitonin, CEA level, testing for RET mutation, and a comprehensive neck ultrasound as soon as the diagnosis is made.
报告一例 Graves 病患者全甲状腺切除术后偶然发现的极罕见的甲状腺髓样癌病例，回顾现有文献，并为读者提供治疗信息。
Graves 病合并甲状腺髓样癌的情况非常罕见。除了我们的病例，文献中总共描述了 15 例，只有 6 例是偶然发现的。
当 Graves 病合并甲状腺髓样癌被偶然发现时，一旦确诊，应立即开始进行术后降钙素、CEA 水平、RET 突变检测和全面的颈部超声等回溯性检查。
