Division of Gastroenterology, Hepatology and Endoscopy, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA, 02115, USA.
Dig Dis Sci. 2022 May;67(5):1660-1673. doi: 10.1007/s10620-022-07426-7. Epub 2022 Apr 16.
The concept of endoscopic lumen apposition has seen a dramatic shift in the last several decades. Early natural orifice trans-luminal endoscopic surgery (NOTES) concepts have transformed into specialized lumen-apposing metal stents (LAMSs) and delivery devices, which provide endoscopists a minimally invasive alternative to surgical intervention. These LAMSs have become the bedrock of therapeutic endoscopy and provide treatment for a wide spectrum of gastrointestinal disorders. In this review, we summarize the changing landscape of therapeutic endoscopy by highlighting the use of LAMS and future directions as well as alternative devices to achieve lumen apposition.
内镜管腔贴合的概念在过去几十年发生了重大变化。早期的经自然腔道内镜外科（NOTES）概念已经转变为专门的管腔贴合金属支架（LAMS）和输送装置，为内镜医生提供了一种微创替代手术干预的方法。这些 LAMS 已成为治疗性内镜的基础，并为广泛的胃肠道疾病提供了治疗。在这篇综述中，我们通过强调 LAMS 的使用以及实现管腔贴合的未来方向和替代设备，总结了治疗性内镜的变化格局。
