Eldine Rakan Nasser, Dehaini Hassan, Hoballah Jamal, Haddad Fady
Division of Vascular & Endovascular Surgery, Department of Surgery, Faculty of Medicine, American University of Beirut, Beirut, Lebanon.
Ann Vasc Dis. 2022 Mar 25;15(1):1-7. doi: 10.3400/avd.ra.21-00055.
Isolated superior mesenteric artery dissection (ISMAD) is a rare pathology with multifactorial etiology. The aim of this article is to provide a narrative review of the latest literature about ISMAD. Case reports, series, and recent meta-analyses were included. This review is introduced with a brief case report of a rare etiology of ISMAD, followed by a discussion of its etiology, clinical presentation, diagnosis, classification, and treatment, and we report a new cause of ISMAD, that is, blunt abdominal trauma. The etiology of ISMAD is multifactorial, consisting of anatomic, genetic, and systemic components. ISMAD is more common among middle-aged males and in East Asia. Its clinical presentation ranges from asymptomatic to mesenteric ischemia, albeit mortality remains <1%. It is diagnosed and classified mostly by computed tomography angiography, and there are five classification systems for ISMAD, though traumatic etiology may be added. The treatment of ISMAD is mostly conservative, with a success rate exceeding 90%. Endovascular stenting is second line, reserved so far for failed medical management, though its role is expanding to include earlier management of symptomatic patients, while open surgical repair is left for acute mesenteric ischemia with bowel compromise.
孤立性肠系膜上动脉夹层(ISMAD)是一种病因多因素的罕见病理情况。本文旨在对有关ISMAD的最新文献进行叙述性综述。纳入了病例报告、系列研究和近期的荟萃分析。本综述首先简要报告一例病因罕见的ISMAD病例,随后讨论其病因、临床表现、诊断、分类和治疗,并且我们报告了ISMAD的一种新病因,即腹部钝性创伤。ISMAD的病因是多因素的,由解剖、遗传和全身因素组成。ISMAD在中年男性和东亚地区更为常见。其临床表现从无症状到肠系膜缺血不等,尽管死亡率仍<1%。它主要通过计算机断层血管造影进行诊断和分类,ISMAD有五种分类系统,不过创伤性病因可能会补充进去。ISMAD的治疗大多是保守的,成功率超过90%。血管内支架置入术是二线治疗方法,目前仅用于药物治疗失败的情况,尽管其作用正在扩大,包括对有症状患者进行早期治疗,而开放性手术修复则用于伴有肠功能障碍的急性肠系膜缺血。