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一种罕见疾病的罕见病因:继发于尿路感染的诱发暴发性紫癜。

A Rare Cause of a Rare Disorder: -Induced Purpura Fulminans Secondary to Urinary Tract Infection.

作者信息

Lowry Jacob, Noel Edva

机构信息

Department of General Surgery, Atrium Health Navicent, 777 Hemlock St, Macon, GA 31201, USA.

Department of Nephrology, Temple University Hospital, 3440 N. Broad Street, Kresge West, Suite 100, PA 19004, USA.

出版信息

Case Rep Crit Care. 2022 Apr 6;2022:9291424. doi: 10.1155/2022/9291424. eCollection 2022.

Abstract

Purpura fulminans is a devastating thrombotic disorder infrequently encountered in medical practice and amongst the medical literature. It is a hematologic emergency in which prompt recognition and initiation of treatment are critical to mitigate its significant morbidity and mortality. Surgical evaluation is commonly required, since the debilitating skin and soft tissue necrosis often degenerate into necrotizing fasciitis, critical limb ischemia, warranting surgical interventions in either a staged or single-step approach. Purpura fulminans can be neonatal, infectious, or idiopathic. Infection-induced purpura fulminans is less common, and only a few microorganisms have been associated with this condition: spp., spp., or spp. This report presents a rare case of induced purpura fulminans. Apart from the unfortunate partial amputation of all left-hand five digits, our patient made a full recovery following effective infectious source control, supportive care with volume resuscitation, anticoagulation, and wound care.

摘要

暴发性紫癜是一种在医学实践和医学文献中很少见的毁灭性血栓形成疾病。它是一种血液学急症,迅速识别并开始治疗对于减轻其显著的发病率和死亡率至关重要。通常需要进行外科评估,因为使人衰弱的皮肤和软组织坏死常常恶化为坏死性筋膜炎、严重肢体缺血,需要采用分期或单步方法进行手术干预。暴发性紫癜可分为新生儿型、感染型或特发性。感染诱发的暴发性紫癜较少见,只有少数微生物与这种情况有关: 属、 属或 属。本报告介绍了一例罕见的感染诱发暴发性紫癜病例。除了不幸地部分截除了左手的所有五个手指外,我们的患者在有效控制感染源、进行容量复苏、抗凝和伤口护理的支持性治疗后完全康复。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de07/9007638/330b2920dbaa/CRICC2022-9291424.001.jpg

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