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由……引起的暴发性紫癜

Fulminans Purpura due to .

作者信息

Guerra Mariana, Marado Daniela

机构信息

Centro Hospitalar Universitário de Coimbra, Coimbra, Portugal.

出版信息

Eur J Case Rep Intern Med. 2022 Nov 21;9(11):003670. doi: 10.12890/2022_003670. eCollection 2022.

Abstract

UNLABELLED

Purpura fulminans (PF) is a dermatological manifestation of a life-threatening condition characterized by disseminated intravascular coagulation and endovascular thrombosis. The idiopathic/infectious form is the most common and usually associated with infection by or . We describe a case of -induced bacteriaemia complicated with PF in an individual who had undergone a recent urinary tract infection intervention. The patient presented with purpuric skin lesions, fever and hypotension but had no alterations in coagulation parameters or disseminated intravascular coagulation. Aggressive early resuscitation, intravenous antibiotics and wound care were essential to a favourable response.

LEARNING POINTS

Purpura fulminans is a dermatological manifestation of an underlying life-threatening condition, and is characterized by disseminated intravascular coagulation and skin necrosis.It is a morbid and potentially fatal condition that can be a cutaneous manifestation of bacteraemia.Early identification and accurate diagnosis of the underlying cause can help minimize morbidity and mortality; management should be tailored to the individual, with the use of intravenous antibiotics, necrotic skin excision and aggressive early resuscitation.

摘要

未标注

暴发性紫癜(PF)是一种危及生命状况的皮肤表现,其特征为弥散性血管内凝血和血管内血栓形成。特发性/感染性形式最为常见,通常与 或 的感染相关。我们描述了一例近期接受尿路感染干预的个体发生 诱导的菌血症并发PF的病例。患者出现紫癜性皮肤病变、发热和低血压,但凝血参数无改变且无弥散性血管内凝血。积极的早期复苏、静脉使用抗生素和伤口护理对于良好的反应至关重要。

学习要点

暴发性紫癜是一种潜在危及生命状况的皮肤表现,其特征为弥散性血管内凝血和皮肤坏死。它是一种严重且可能致命的状况,可为菌血症的皮肤表现。早期识别和准确诊断潜在病因有助于将发病率和死亡率降至最低;管理应因人而异,采用静脉使用抗生素、切除坏死皮肤和积极的早期复苏措施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7ba/9728211/ad377e730b13/3670_Fig1.jpg

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