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破裂颅内动脉瘤患者的血管内治疗:14年间治疗的468例患者系列研究

Endovascular Treatment of Patients with Ruptured Intracranial Aneurysms: A Series of 468 Patients Treated Over a 14-Year Period.

作者信息

Hulscher Franny, Mine Benjamin, Elens Stéphanie, Bonnet Thomas, Suarez Juan Vazquez, Lubicz Boris

机构信息

Hopital Erasme, BE.

出版信息

J Belg Soc Radiol. 2022 Mar 28;106(1):11. doi: 10.5334/jbsr.2550. eCollection 2022.

Abstract

PURPOSE

Non-traumatic subarachnoid hemorrhage (SAH) is an emergency usually caused by the rupture of a saccular intracranial aneurysm. Endovascular treatment (EVT) is now considered as the first therapeutic option. The aim of our study is to evaluate, over a 14-year period in a single center, the result of EVT of ruptured intracranial aneurysms.

METHODS

From the retrospective analysis of our prospectively maintained database, we collected data of 457 patients successfully treated by endovascular approach for a SAH. Descriptive statistics and percentages were used to report clinical and anatomical outcomes, procedure-related complications, post procedural events, morbidity and mortality.

RESULTS

EVT was unsuccessful in eleven patients but effective in 457 patients with two patients who experienced a rebleeding (0.4%). In 6.3% of cases, a second EVT was necessary. The final aneurysm occlusion was complete (65.7%), with a neck remnant (28.2%) or incomplete (6.1%). Procedure-related complications occurred in 5.9% of patients and were associated with five clinical worsening and one death. Overall EVT-related morbidity and mortality were thus of 1.3% and 0.4% respectively. At discharge, 71% of patients had a good recovery (mRS 0-2), 11.2% had a poor outcome (mRS 3-5), and 17.8% died.

CONCLUSION

This study seems to prove that high-volume centers with experienced interventional neuroradiologists carry low rates of technical failure and complication from EVT of ruptured intracranial aneurysm.

摘要

目的

非创伤性蛛网膜下腔出血(SAH)是一种通常由颅内囊状动脉瘤破裂引起的急症。血管内治疗(EVT)目前被视为首选治疗方案。我们研究的目的是评估在单一中心14年期间颅内破裂动脉瘤的血管内治疗结果。

方法

通过对我们前瞻性维护的数据库进行回顾性分析,我们收集了457例通过血管内方法成功治疗SAH患者的数据。描述性统计和百分比用于报告临床和解剖学结果、与手术相关的并发症、术后事件、发病率和死亡率。

结果

11例患者血管内治疗未成功,但457例患者治疗有效,其中2例发生再出血(0.4%)。6.3%的病例需要进行第二次血管内治疗。最终动脉瘤闭塞完全(65.7%),有颈部残余(28.2%)或不完全闭塞(6.1%)。5.9%的患者发生了与手术相关的并发症,与5例临床病情恶化和1例死亡相关。因此,总体血管内治疗相关的发病率和死亡率分别为1.3%和0.4%。出院时,71%的患者恢复良好(改良Rankin量表评分0 - 2),11.2%的患者预后不良(改良Rankin量表评分3 - 5),17.8%的患者死亡。

结论

本研究似乎证明,拥有经验丰富的介入神经放射科医生的大容量中心,颅内破裂动脉瘤血管内治疗的技术失败率和并发症发生率较低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df81/8973758/c479e1b71ac5/jbsr-106-1-2550-g1.jpg

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