Discipline of Physiotherapy, Trinity Centre for Health Sciences, Trinity College Dublin, Dublin Ireland.
Department of Medical Gerontology, Trinity College Dublin, Dublin, Ireland.
Curr Aging Sci. 2022 Aug 4;15(3):198-208. doi: 10.2174/1874609815666220419102648.
This review outlines the normal heart rate and blood pressure response to active standing, the physiological mechanisms governing these, and the effect of ageing on the responses.
A literature search was conducted to identify articles investigating the normal heart rate and/or blood pressure response to standing.
Heart rate when standing increases and then decreases and recovers to baseline. Blood pressure responses are inverse. Skeletal muscle contraction and the baroreceptor reflex drive this. With ageing, heart rate response attenuates and the initial blood pressure response increases.
Normal heart rate and blood pressure responses are attributed to the baroreceptor reflex and skeletal muscle contraction. Decreased muscle strength and baroreceptor sensitivity are associated with ageing, suggesting a possible benefit in improving skeletal muscle strength to maintain an efficient response. Understanding these responses and their variation with ageing is clinically relevant and may be beneficial in improving rehabilitation outcomes.
本文概述了主动站立时正常心率和血压的反应、控制这些反应的生理机制，以及年龄对这些反应的影响。
对研究主动站立时正常心率和/或血压反应的文章进行了文献检索。
站立时心率先增加后减少，然后恢复到基线水平。血压反应相反。骨骼肌收缩和压力感受器反射驱动这种变化。随着年龄的增长，心率反应减弱，初始血压反应增加。
正常的心率和血压反应归因于压力感受器反射和骨骼肌收缩。肌肉力量和压力感受器敏感性的下降与年龄有关，这表明改善骨骼肌力量以维持有效反应可能是有益的。了解这些反应及其随年龄的变化具有临床意义，可能有助于改善康复效果。
