Kumamoto Kodai, Sato Hideaki, Tsutsui Yuji, Awamoto Shinichi, Yamashita Yasuo, Baba Shingo, Sasaki Masayuki
Kyushu University, Japan.
Junshin Gakuen University.
J Nucl Med Technol. 2022 Apr 19. doi: 10.2967/jnmt.121.263240.
This study investigated the spatial resolution and image quality of the continuous bed motion (CBM) method in a sensitive silicon photomultiplier (SiPM)-based positron emission tomography (PET)/computed tomography (CT) system compared with the traditional step-and-shoot (SS) method. Siemens Biograph Vision was used in this study. Data acquisition using the SS method was performed for 3 min per bed. In the CBM method, the bed speed ranged from 0.5 to 3.3 mm/s. The acquisition time equivalent to the SS method was 1.1 mm/s for 2-bed ranges and 0.8 mm/s for seven-bed ranges. The spatial resolution was investigated using F point sources and evaluated using the full width at half maximum. Image quality was investigated using a National Electrical Manufacturers Association International Electrotechnical Commission body phantom with six spheres 10-, 13-, 17-, 22-, 28-, and 37-mm inner diameters. The radioactivity concentration ratio of the F solution in all spheres and the background was approximately 4:1. The detectability of each sphere was visually evaluated on a five-step score. Image quality was physically evaluated using the noise equivalent count rate (NECphantom), contrast percentage of the 10-mm hot sphere (QH,10mm), background variability percentage (N10mm), and contrast-noise ratio (QH,10mm/N10mm). The spatial resolution was not affected by the difference of acquisition methods and bed speeds. The detectability of the 10-mm sphere with a bed speed of 2.2 mm/s or faster was significantly inferior to that of the SS 2-bed method. In evaluating image quality, no significant difference in the contrast percentage was observed among the acquisition methods and speeds in the CBM method. However, the increasing bed speed in the CBM method increased the N10mm and decreased the NECphantom. When comparing the SS 2-bed method with the CBM method at 0.8 mm/s, no significant differences in all parameters were observed. In a SiPM-based PET/CT scanner, the CBM method provides equivalent spatial resolution and image quality in whole body PET images with same acquisition time using the SS method.
本研究调查了基于灵敏硅光电倍增管(SiPM)的正电子发射断层扫描(PET)/计算机断层扫描(CT)系统中连续床位移动(CBM)方法的空间分辨率和图像质量,并与传统的步进-采集(SS)方法进行了比较。本研究使用了西门子Biograph Vision。使用SS方法进行数据采集时,每个床位采集3分钟。在CBM方法中,床位速度范围为0.5至3.3毫米/秒。与SS方法等效的采集时间,在2个床位范围时为1.1毫米/秒,在7个床位范围时为0.8毫米/秒。使用F点源研究空间分辨率,并使用半高全宽进行评估。使用带有六个内径分别为10、13、17、22、28和37毫米球体的美国国家电气制造商协会国际电工委员会体模研究图像质量。所有球体中F溶液与背景的放射性浓度比约为4:1。通过五步评分法对每个球体的可探测性进行视觉评估。使用噪声等效计数率(NEC体模)、10毫米热球体的对比度百分比(QH,10mm)、背景变化百分比(N10mm)和对比度-噪声比(QH,10mm/N10mm)对图像质量进行物理评估。空间分辨率不受采集方法和床位速度差异的影响。床位速度为2.2毫米/秒或更快时,10毫米球体的可探测性明显低于SS 2床位方法。在评估图像质量时,CBM方法中不同采集方法和速度之间的对比度百分比没有显著差异。然而,CBM方法中床位速度的增加会使N10mm增加,NEC体模降低。将SS 2床位方法与0.8毫米/秒的CBM方法进行比较时,所有参数均未观察到显著差异。在基于SiPM的PET/CT扫描仪中,CBM方法在与SS方法相同采集时间的全身PET图像中提供了等效的空间分辨率和图像质量。