Department of Craniomaxillofacial Surgery, Plastic Surgery Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100144, China.
Chin Med J (Engl). 2022 Apr 20;135(8):971-976. doi: 10.1097/CM9.0000000000002116.
Hemifacial microsomia (HFM), which involves multiple sites with different levels of severity, is the second most common congenital craniofacial deformity after cleft lip and palate. However, three-dimensional (3D) measurements of mandibular deformities have not yet been studied in detail. The objective of this study is to investigate the method of 3D measurements of mandibular deformities in HFM patients.
A total of 48 HFM patients were included in this study. All clinical treatment for patients was performed in the Plastic Surgery Hospital of the Chinese Academy of Medical Sciences at Peking Union Medical College from June 2006 to June 2020. The patients' 3D computerized tomography scan data were processed using medical imaging software, following four iterative steps: 3D reconstruction, mirroring, differential analysis, and partition.
The characteristics of the mandibular bone in HFM patients are mainly presented as follows: (1) compared to the normal side, the part of the bone body that extends from the ascending ramus to the pogonion (Po-NB) is analyzed using a dynamic process: less fullness-fullness-more fullness; (2) absences were frequently observed among the angular zones, that is, the height of the ascending ramus is deficient.
HFM is a complicated condition with numerous variations in clinical presentation. We employed both 3D image reconstruction and computerization image processing techniques to investigate asymmetrical mandibular deformity in HFM patients in detail and with great accuracy. This will be of great use to clinicians for disease management.
半侧颜面短小症（HFM）涉及多个部位，严重程度不一，是继唇腭裂之后第二常见的颅面先天畸形。然而，下颌骨畸形的三维（3D）测量尚未得到详细研究。本研究旨在探讨 HFM 患者下颌骨畸形的 3D 测量方法。
本研究共纳入 48 例 HFM 患者。所有患者的临床治疗均于 2006 年 6 月至 2020 年 6 月在中国医学科学院整形外科医院北京协和医学院完成。使用医学成像软件对患者的 3D 计算机断层扫描数据进行处理，包括四个迭代步骤：3D 重建、镜像、差分分析和分区。
HFM 患者下颌骨的特征主要表现为：（1）与正常侧相比，升支至颏点（Po-NB）的骨体部分采用动态过程进行分析：从饱满-饱满-更饱满；（2）角区经常缺失，即升支高度不足。
HFM 是一种临床表现复杂、变化多样的疾病。我们采用 3D 图像重建和计算机图像处理技术，详细、准确地研究了 HFM 患者的不对称下颌骨畸形。这将对临床医生的疾病管理有很大帮助。
