一种简单的碘-DMSO 促进的多组分反应，用于合成 2,4-二取代的二氢三唑-3-酮。
A simple iodine-DMSO-promoted multicomponent reaction for the synthesis of 2,4-disubstituted dihydrotriazole-3-ones.
机构信息
Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, 1838 Guangzhou Avenue North, Guangzhou 510515, China.
出版信息
Org Biomol Chem. 2022 May 11;20(18):3721-3725. doi: 10.1039/d2ob00352j.
PMID:35442256
Abstract
A series of 2,4-disubstituted 1,2,4-triazole-3-ones 4 were prepared an iodine-DMSO-promoted three-component reaction of formaldehyde, amines and hydrazines in moderate yields.
摘要
一系列 2,4-二取代的 1,2,4-三唑-3-酮 4 通过碘-DMSO 促进的甲醛、胺和肼的三组分反应以中等产率制备。
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