Li Z H, Zhao Q, Gong D G, Sun Y X, Shen P, Lin Hongbo, He Na
Department of Epidemiology, Key Laboratory of Public Health Safety of Ministry of Education, School of Public Health, Fudan University, Shanghai 200032, China.
Department of Data Center, Ningbo Yinzhou District Center for Disease Control and Prevention, Ningbo 315100, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2022 Apr 10;43(4):541-547. doi: 10.3760/cma.j.cn112338-20210719-00564.
To understand the hospitalization rates and influencing factors after diagnosis among HIV infection cases, based on real-world data in Yinzhou district of Ningbo. A retrospective cohort study was conducted based on the databases of National AIDS Comprehensive Response Information Management System and Yinzhou Health Information Platform. The information about the following-up results, antiviral treatment data, electronic records of inpatient of the HIV cases reported during 2012-2020 were collected to analyze the rates, causes and influencing factors of hospitalization. Among the 763 HIV infection cases reported in Yinzhou from 2012 to 2020, the hospitalization rate was 6.95% (53/763), and the number of inpatient was 2.59 per 100 person years. The hospitalization rate and the number of hospitalization per 100 person years in HIV infection cases were 3.16% (10/316) and 0.81 in those aged <30 years, 6.07% (15/247) and 1.59 in those aged >30 years, 7.86% (11/140) and 4.05 in those aged >45 years and 28.33% (17/60) and 17.40 in those aged ≥60 years respectively. Logistic multivariate regression analysis indicated that being aged ≥60 years was the influencing factor for hospitalizations in HIV infection cases (а=14.44, 95%:3.57-58.46). The hospitalization rates due to AIDS related diseases, cardiovascular diseases and metabolic diseases, and other diseases were 1.83% (14/763), 1.05% (8/763), and 3.93% (30/763), respectively. The hospitalization burden due to HIV infection was still mainly caused by those aged ≥60 years in Yinzhou, similar to that in general population and less proportion of hospitalizations were due to AIDS related diseases. The overall increase of hospitalizations due to AIDS was not obvious in Yinzhou.
为了解宁波市鄞州区HIV感染病例确诊后的住院率及影响因素，基于真实世界数据进行研究。以国家艾滋病综合防治信息管理系统数据库和鄞州区健康信息平台为基础开展回顾性队列研究。收集2012 - 2020年期间报告的HIV病例的随访结果、抗病毒治疗数据、住院电子记录，分析住院率、原因及影响因素。2012年至2020年鄞州区报告的763例HIV感染病例中，住院率为6.95%（53/763），每100人年住院人次为2.59。<30岁的HIV感染病例住院率和每100人年住院人次分别为3.16%（10/316）和0.81，>30岁者分别为6.07%（15/247）和1.59，>45岁者分别为7.86%（11/140）和4.05，≥60岁者分别为28.33%（17/60）和17.40。多因素Logistic回归分析显示，≥60岁是HIV感染病例住院的影响因素（а=14.44，95%可信区间：3.57 - 58.46）。因艾滋病相关疾病、心血管疾病和代谢性疾病及其他疾病住院率分别为1.83%（14/763）、1.05%（8/763）和3.93%（30/763）。鄞州区HIV感染住院负担仍主要由≥60岁人群引起，与一般人群相似，因艾滋病相关疾病住院比例较少。鄞州区艾滋病住院总体增幅不明显。
