Adichunchanagiri Institute of Medical Sciences, Mandya.
J Assoc Physicians India. 2022 Apr;70(4):11-12.
Chronic pancreatitis is characterized by pancreatic inflammatory and fibrotic injury that results in loss of pancreatic structure both exocrine and endocrine functions, often leading to complications like glucose intolerance and Diabetes Mellitus. Diabetes secondary to pancreatic diseases is classified as pancreatic diabetes or type 3c diabetes. Diabetes secondary to chronic pancreatitis differs metabolically and clinically from other types of Diabetes Mellitus. In chronic pancreatitis there is loss of Beta cell mass along with alpha and other cell masses. Pancreatic Diabetes is characterized by impaired Insulin secretion in response to ingestion of meal. Type 3c Diabetes accounts for 5-10% of all cases of diabetes in Western Population. In this Cross Sectional study patients presenting to a tertiary care centre with typical clinical and radiological features of Chronic pancreatitis were investigated for the prevalence of Diabetes Mellitus. CT scan was used as the imaging modality of choice to detect Chronic Pancreatitis. Material: In this Cross Sectional study 60 patients who presented with typical clinical and radiological features of Chronic pancreatitis were investigated for Diabetes Mellitus. CT scan was used as the imaging modality of choice to detect Chronic Pancreatitis. Observation: The prevalence of Diabetes Mellitus in patients of Chronic Pancreatitis in our study was 61.6%. The prevalence of exocrine insufficiency in patients of Chronic pancreatitis in our study was 68.3% Conclusion: Diabetes Mellitus should be specifically sought for while managing the pain of Chronic Pancreatitis patient.
慢性胰腺炎的特征是胰腺炎症和纤维化损伤,导致外分泌和内分泌功能的胰腺结构丧失,常导致葡萄糖不耐受和糖尿病等并发症。由胰腺疾病引起的糖尿病被归类为胰腺性糖尿病或 3c 型糖尿病。慢性胰腺炎引起的糖尿病在代谢和临床方面与其他类型的糖尿病不同。在慢性胰腺炎中,β细胞质量以及α和其他细胞质量会丧失。胰腺性糖尿病的特征是在摄入餐后胰岛素分泌受损。3c 型糖尿病占西方人群所有糖尿病病例的 5-10%。在这项横断面研究中,对就诊于三级护理中心的具有慢性胰腺炎典型临床和放射学特征的患者进行了糖尿病患病率调查。CT 扫描被用作检测慢性胰腺炎的首选影像学方法。
在这项横断面研究中,对 60 例具有慢性胰腺炎典型临床和放射学特征的患者进行了糖尿病患病率调查。CT 扫描被用作检测慢性胰腺炎的首选影像学方法。
在我们的研究中,慢性胰腺炎患者中糖尿病的患病率为 61.6%。在我们的研究中,慢性胰腺炎患者外分泌功能不全的患病率为 68.3%。
在治疗慢性胰腺炎患者的疼痛时,应特别注意寻找糖尿病。