JSS Medical College, Mysuru.
J Assoc Physicians India. 2022 Apr;70(4):11-12.
Reduction in lung function in diabetics is observed in previous studies. Diabetes-related muscle weakness has been reported previously. The reduced muscle strength in diabetics may also affect the respiratory muscles and contribute to a better understanding of the mechanism behind decreased lung function and its clinical relevance. The objective of this study is to find the association between handgrip strength and pulmonary functions in subjects with and without DM.
Case-control study assessing 115 diabetics and 115 nondiabetics of age 18-60 years was done. FBS, PPBS, HbA1c was done to differentiate diabetics and nondiabetics. PFT was performed using spirometry and handgrip strength was measured using an electronic hand dynamometer.
Mean handgrip strength among diabetics was 29.3kg (SD 5.23) and among nondiabetics was 32.17kg(SD 8.43). The mean FEV1 in diabetics (2.18 L) was lesser than in nondiabetics (2.37 L). This association was statistically significant with p<0.05. Mean FVC among diabetics (2.63 L) was lesser than in nondiabetics (2.85 L). It was statistically significant with p<0.05. The Pearson correlation coefficient of FEV1 and grip strength among diabetics was found to be positive (r =0.518) and statistically significant (p =0.001). Also, for FVC and handgrip strength, there was a positive correlation (r = 0.49), which was statistically significant(p=0.001). Even in nondiabetics, the Pearson correlation coefficient of FEV1 and grip strength was found to be positive (r =0.633) and statistically significant (p =0.001). Also, for FVC and handgrip strength there was a positive correlation (r = 0.631) among nondiabetics which was statistically significant(p=0.001).
Pulmonary function parameters FEV1 and FVC were reduced in diabetics compared with nondiabetics. In diabetics, handgrip strength appears to be reduced compared to nondiabetics. Our study concluded that there is a reduction in lung functions in people with low handgrip strength in both diabetics and nondiabetics.
探讨糖尿病患者的握力与肺功能之间的关系。
本研究为病例对照研究，纳入 115 例糖尿病患者和 115 例非糖尿病患者，分别测量其空腹血糖、餐后 2 小时血糖、糖化血红蛋白、肺功能及握力。
糖尿病组的平均握力为 29.3kg（SD 5.23），非糖尿病组为 32.17kg（SD 8.43），糖尿病组的 FEV1（2.18L）明显低于非糖尿病组（2.37L），差异有统计学意义（p<0.05）。糖尿病组的 FVC（2.63L）明显低于非糖尿病组（2.85L），差异有统计学意义（p<0.05）。糖尿病患者的 FEV1 和握力呈正相关（r=0.518，p=0.001），FVC 和握力也呈正相关（r=0.49，p=0.001）。非糖尿病患者的 FEV1 和握力呈正相关（r=0.633，p=0.001），FVC 和握力也呈正相关（r=0.631，p=0.001）。
糖尿病患者的肺功能参数 FEV1 和 FVC 低于非糖尿病患者，且糖尿病患者的握力较非糖尿病患者降低。我们的研究表明，无论是否患有糖尿病，握力较低的人群肺功能均降低。
