Jawaharlal Nehru Medical College, Belgaum.
J Assoc Physicians India. 2022 Apr;70(4):11-12.
Systemic Hypertension (HTN) is one of the most common co-morbidities in Diabetes Mellitus (DM). Because of the drawbacks of office blood pressure monitoring, it has been suggested that ambulatory blood pressure monitoring (ABPM) be used for hypertension assessment. The sensitivity of Clinic/Office monitoring of BP to predict hypertension-associated organ damage is less. Hence the present study was carried out to estimate the prevalence of hypertension in normotensive type 2 diabetic patients by using a 24-hour ambulatory blood pressure machine and also to assess the relationship between blood pressure patterns and anthropometric measurements in overweight and obese type 2 diabetic patients.
A 1 year cross-sectional hospital-based study was conducted on 162 people, attending a tertiary care institute over the age of 18, who had type 2 diabetes and a Body Mass Index (BMI) of 25 to 40 kg/m2 (Asian cut-off > 23 kg/m2). All subjects underwent a standardized medical examination including anthropometric measurements, laboratory investigations and 24 hour ambulatory blood pressure monitoring. Descriptive analysis was carried out by mean and standard deviation for quantitative variables, frequency, and proportion for categorical variables. P value <0.05 was considered statistically significant.
The mean age was 60.65 ± 11.46 years. Majority were males (62.35%). The mean BMI was 28.31 ± 2.15 kg/m2. The mean all day SBP was 133.66 ± 13.53 mm/ hg while the mean all day DBP was 76.45 ± 10.99 mm/hg. The prevalence of HTN as measured by all day SBP was 77.78% while it was 42.59% for all day DBP. Systolic non dipping was seen in 93.39% of overweight and 90.24% of obese subjects as classified by BMI, respectively. Diastolic non-dipping was seen in 76.86% of overweight and 73.17% of obese subjects as classified by BMI, respectively. There was a statistically significant association between all-day SBP, all-day DBP, day SBP and day DBP with BMI (P Value<0.05) in males. But in females, there was a statistically significant association between all day SBP, day SBP with BMI only (P Value<0.05).
The present study was one of the kinds in the study region as there was no report of ABPM parameters in the study population. Patients with T2DM can benefit from routine ABPM by early identification and management of Hypertension in Type 2 DM.
通过使用 24 小时动态血压监测仪评估超重和肥胖 2 型糖尿病患者的血压模式与人体测量学指标之间的关系,来估计正常血压 2 型糖尿病患者中高血压的患病率。
这是一项在 1 家三级保健机构进行的 1 年时间的横断面医院研究,共纳入 162 名年龄在 18 岁以上、患有 2 型糖尿病且体重指数(BMI)为 25 至 40kg/m2(亚洲切点>23kg/m2)的患者。所有患者均接受标准化的体格检查,包括人体测量学检查、实验室检查和 24 小时动态血压监测。定量变量采用均值和标准差进行描述性分析,定性变量采用频率和比例进行描述性分析。P 值<0.05 被认为具有统计学意义。
患者的平均年龄为 60.65±11.46 岁,其中大多数为男性(62.35%)。平均 BMI 为 28.31±2.15kg/m2。平均 24 小时收缩压为 133.66±13.53mmHg,平均 24 小时舒张压为 76.45±10.99mmHg。根据 24 小时收缩压测量的高血压患病率为 77.78%,根据 24 小时舒张压测量的高血压患病率为 42.59%。根据 BMI 分类,超重患者中分别有 93.39%和 90.24%存在收缩压非杓型,肥胖患者中分别有 93.39%和 90.24%存在收缩压非杓型。男性中,24 小时收缩压、24 小时舒张压、日间收缩压和日间舒张压与 BMI 之间存在统计学显著关联(P 值<0.05)。但在女性中,仅 24 小时收缩压和日间收缩压与 BMI 之间存在统计学显著关联(P 值<0.05)。
本研究在该研究区域内进行,因为之前没有关于该研究人群的 ABPM 参数的报告。通过早期识别和管理 2 型糖尿病患者的高血压,2 型糖尿病患者可从常规 ABPM 中获益。