Gandhi Medical College, Mandsaur, Bhopal.
J Assoc Physicians India. 2022 Apr;70(4):11-12.
Metabolic syndrome has been observed in patients with vitiligo. Literature suggest that there is some link between vitiligo and metabolic syndrome. Autoimmunity, oxidative stress and decreased number of melanocytes are involved in its pathogenesis. This study aimed to assess metabolic syndrome in patients of vitiligo, its association with different types of vitiligo, age of patients and duration of vitiligo.
We enrolled 62 vitiligo patients who met inclusion criteria in this cross sectional study from 1st august 2020 to 31st July 2021. Detailed history, physical examination and blood investigations were done in all patients and NCEP ATP III criteria was used for diagnosis of metabolic syndrome.
Mean age of participants 35.98±15.48 years; M:F:: 1:2.3. Metabolic syndrome was observed in 12.9% vitiligo patients. Advancing age and non segmental vitiligo were significantly associated with metabolic syndrome (p<0.05).
Vitiligo is a condition which may affect individual at any age and carries risk of developing metabolic syndrome in future. In our study Metabolic syndrome is observed in 12.9% patients with vitiligo. Early identification of metabolic syndrome and appropriate management of such patients may help in reducing cardiovascular morbidity and mortality. Further prospective studies required to establish relation between vitiligo and metabolic syndrome.
评估白癜风患者代谢综合征的发病情况,及其与白癜风不同类型、患者年龄和白癜风病程的关系。
本横断面研究纳入了 2020 年 8 月 1 日至 2021 年 7 月 31 日期间符合纳入标准的 62 例白癜风患者。所有患者均进行详细的病史询问、体格检查和血液学检查,并采用 NCEP ATP III 标准诊断代谢综合征。
参与者的平均年龄为 35.98±15.48 岁;男女比例为 1:2.3。12.9%的白癜风患者存在代谢综合征。年龄增长和非节段性白癜风与代谢综合征显著相关(p<0.05)。
白癜风是一种可能在任何年龄影响个体的疾病,未来存在发生代谢综合征的风险。在我们的研究中,12.9%的白癜风患者存在代谢综合征。早期识别代谢综合征并对这些患者进行适当的管理,可能有助于降低心血管疾病的发病率和死亡率。需要进一步的前瞻性研究来确定白癜风和代谢综合征之间的关系。