Elassal Ahmed Abdelrahman, Al-Radi Osman Osama, Debis Ragab Shehata, Zaher Zaher Faisal, Abdelmohsen Gaser Abdelmohsen, Faden Mazen Shamsaldeen, Noaman Nada Ahmed, Elakaby Ahmed Ragab, Abdelmotaleb Mohamed Esam, Abdulgawad Ahmed Mostafa, Elhudairy Mohamed Saleh, Jabbad Abdulla Husain, Ismail Ahmed Abdelaziz, Aljohani Norah Bakheet, Alghamdi Arwa Mohammed, Dohain Ahmed Mohamed
Cardiac Surgery Unit, Department of Surgery, King Abdulaziz University, Jeddah, 21589, Saudi Arabia.
Cardiothoracic Surgery Department, Zagazig University, Zagazig, Egypt.
J Cardiothorac Surg. 2022 Apr 20;17(1):80. doi: 10.1186/s13019-022-01830-w.
Many studies still dispute the identification of independent risk factors that influence outcome after neonatal cardiac surgery. We present our study to announce the contemporary outcomes and risk profile of neonatal cardiac surgery at our institute.
We designed a retrospective study of neonatal patients who underwent surgery for congenital heart diseases between June 2011 and April 2020. Demographic, operative, and postoperative data were collected from medical records and surgical databases. The primary outcome was the operative mortality (in-hospital death) and secondary outcomes included hospital length of stay, intensive care unit stay, duration of mechanical ventilation.
In total, 1155 cardiac surgeries in children were identified; of these, 136 (11.8%) were performed in neonates. Arterial switch operations (48 cases) were the most frequent procedures. Postoperatively, 11 (8.1%) patients required extracorporeal membrane oxygenation, and 4 (2.9%) patients had complete heart block. Postoperative in-hospital mortality was 11%. The median postoperative duration of mechanical ventilation, intensive care unit stay, and hospital length of stay were 6, 18, and 24 days, respectively.
The early outcomes of neonatal cardiac surgery are encouraging. The requirement of postoperative extracorporeal membrane oxygenation support, postoperative intracranial hemorrhage, and acute kidney were identified as independent risk factors of mortality following surgery for congenital heart defects in neonates.
许多研究仍在对影响新生儿心脏手术后预后的独立危险因素的识别存在争议。我们开展本研究以公布我院新生儿心脏手术的当代疗效及风险概况。
我们设计了一项对2011年6月至2020年4月期间接受先天性心脏病手术的新生儿患者的回顾性研究。从病历和手术数据库中收集人口统计学、手术及术后数据。主要结局为手术死亡率（住院死亡），次要结局包括住院时间、重症监护病房停留时间、机械通气持续时间。
共确定了1155例儿童心脏手术；其中，136例（11.8%）为新生儿手术。动脉调转术（48例）是最常见的手术方式。术后，11例（8.1%）患者需要体外膜肺氧合，4例（2.9%）患者发生完全性心脏传导阻滞。术后住院死亡率为11%。术后机械通气、重症监护病房停留及住院时间的中位数分别为6天、18天和24天。
新生儿心脏手术的早期疗效令人鼓舞。术后体外膜肺氧合支持的需求、术后颅内出血和急性肾损伤被确定为新生儿先天性心脏病手术后死亡的独立危险因素。
