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一名局部使用类固醇药物过度的儿科患者的库欣综合征

Cushing Syndrome in a Pediatric Patient with Topical Steroid Overuse.

作者信息

Kuikel Sandip, Aryal Sunil, Basnyat Rupesh Shingh, Rimal Suman

机构信息

Shishuwa Hospital, 33700 Pokhara, Nepal.

Department of Internal Medicine, Tribhuvan University Institute of Medicine, 44600 Kathmandu, Nepal.

出版信息

Case Rep Endocrinol. 2022 Apr 11;2022:8487737. doi: 10.1155/2022/8487737. eCollection 2022.

Abstract

Cushing syndrome is a state of hypercortisolism from exogenous or endogenous exposure to glucocorticoids resulting in various clinical manifestations. In this case report, we present a case of a 15-month-old child who presented with cushingoid facies due to over-the-counter misuse of a very potent topical steroid (clobetasol 0.05%) for suspected scabies. Laboratory measurement of urinary free cortisol level was low, and 8 : 00 am basal cortisol level was measured, which was decreased, which confirmed the diagnosis of Cushing syndrome due to exogenous source. Over-the-counter topical steroids should not be used, and one should always consult a registered medical practitioner before using such products. Physicians when prescribing topical steroids should warn patients about the potential side effects of prolonged use of topical steroids.

摘要

库欣综合征是由于外源性或内源性接触糖皮质激素导致皮质醇增多,从而引发各种临床表现的一种病症。在本病例报告中,我们呈现了一名15个月大儿童的病例,该儿童因疑似疥疮而自行滥用强效外用类固醇(0.05%丙酸氯倍他索),出现了库欣样面容。实验室检测尿游离皮质醇水平较低,并测量了上午8点的基础皮质醇水平,该水平降低,这证实了外源性库欣综合征的诊断。非处方外用类固醇不应使用,在使用此类产品前应始终咨询注册医生。医生在开具外用类固醇处方时,应告知患者长期使用外用类固醇的潜在副作用。

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