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妊娠期血小板减少症:近期进展综述

Gestational Thrombocytopenia: A Review on Recent Updates.

作者信息

Habas Elmukhtar, Rayani Amnna, Alfitori Gamal, Eldin Ahmed Gamal, Elzouki Abdel-Naser Y

机构信息

Internal Medicine, Hamad Medical Corporation, Doha, QAT.

Internal Medicine, Hamad General Hospital, Doha, QAT.

出版信息

Cureus. 2022 Mar 16;14(3):e23204. doi: 10.7759/cureus.23204. eCollection 2022 Mar.

Abstract

Thrombocytopenia is a condition in which the blood platelet count is low. It is well established that the mild thrombocytopenia frequency is higher in normal pregnancy. This type of thrombocytopenia was named pregnancy-induced thrombocytopenia. However, recently, it has been widely known as gestational thrombocytopenia (GT). The rate is higher in women with a prior GT history and multiple pregnancies. However, it appears that GT is a physiological response to the pregnancy; placenta's peculiar structure and its unique blood flow pattern play major roles in GT development. There are no specific, precise, or known underlying pathophysiological mechanisms of GT, and no new specific management strategies are published yet. Therefore, we decided to do a non-systematic review of any recent updates that had been published in PubMed, EMBASE, and Web of Science about the pathophysiology of GT, its treatment, and other related topics.

摘要

血小板减少症是一种血小板计数偏低的病症。众所周知,正常妊娠中轻度血小板减少症的发生率更高。这种类型的血小板减少症被称为妊娠性血小板减少症。然而,最近它被广泛称为妊娠期血小板减少症(GT)。既往有GT病史和多胎妊娠的女性中该发生率更高。然而,GT似乎是对妊娠的一种生理反应;胎盘独特的结构及其独特的血流模式在GT的发生中起主要作用。GT尚无具体、精确或已知的潜在病理生理机制,且尚未公布新的具体管理策略。因此,我们决定对PubMed、EMBASE和科学网最近发表的关于GT的病理生理学、治疗及其他相关主题的任何最新进展进行非系统性综述。

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