Weene L E
Ann Ophthalmol. 1978 Apr;10(4):513-9.
Wound healing in 350 cases of senile cataract extraction done with a corneal incision without a conjunctival flap and closed with 3 deep 6-0 chromic gut sutures is examined. There were no cases of epithelial downgrowth and a low incidence of conjunctival blebs. There was one case of endothalmitis and 4 of iris prolapse. Sutures fell out between the 9th and 16th days and the large knots did not cause excessive irritation while in place. There was an 18% incidence of wound leak manifested by shallow or flat anterior chamber. All of these anterior chambers reformed spontaneously soon after the sutures fell out, indicating the wound leak was probably along the sutures tract. One patient with wound leak developed mild glaucoma postoperatively. Wound healing after cataract surgery is discussed. Epithelial downgrowth and conjunctival blebs are related more to tight silk sutures than absence of conjunctival flap. The early loss of the gut sutures does not decrease wound strength since the sutures have already lost their tensile strength. The epithelium which grows into the cataract wound postoperatively when a flap is not used activates stromal fibrocytes and covers any delayed iris prolapse.
对350例行角膜切口、不做结膜瓣且用3根6-0号深层铬制肠线缝合关闭的老年性白内障摘除术患者的伤口愈合情况进行了检查。未发生上皮内生病例,结膜下积液发生率低。发生1例眼内炎和4例虹膜脱出。缝线在第9至16天脱落,大结在位时未引起过度刺激。有18%的伤口渗漏发生率,表现为前房浅或扁平。所有这些前房在缝线脱落后不久均自行恢复,表明伤口渗漏可能沿缝线通道发生。1例伤口渗漏患者术后发生轻度青光眼。对白内障手术后的伤口愈合情况进行了讨论。上皮内生和结膜下积液与丝线缝合过紧的关系比与未做结膜瓣的关系更大。肠线缝线早期脱落不会降低伤口强度,因为缝线已经失去了抗张强度。在不做瓣的情况下,术后长入白内障伤口的上皮会激活基质纤维细胞,并覆盖任何延迟发生的虹膜脱出。