Department of Neurology, Hebei Provincial People's Hospital, Shijiazhuang, Hebei, 050000, China.
Department of Oncology, Hebei Provincial People's Hospital, Shijiazhuang, Hebei, 050001, China.
Medicine (Baltimore). 2022 Apr 8;101(14):e28968. doi: 10.1097/MD.0000000000028968.
Acute cerebral artery occlusion is a common disease with high morbidity and mortality. At present, the commonly used mechanical thrombectomy schemes are mechanical thrombectomy and stent thrombectomy. However, the clinical differences between the two methods is not fully understood. The present study aimed to evaluate the clinical effectiveness of Solitaire AB stent thrombectomy for acute cerebral infarction (ACI).
A retrospective study was carried out in 96 ACI patients admitted to our department from January 2017 to January 2020. According to the treatment they received, they were divided into group A (conventional microcatheter mechanical thrombectomy, n = 48) and group B (Solitaire AB stent thrombectomy, n = 48). All patients were followed up for 3 months. Their pre- and post-operative nerve function indices were compared between the 2 groups. The therapeutic effects were evaluated by thrombolysis in cerebral infarction scale system, Glasgow coma scale (GCS), National Institutes of Health Stroke Scale (NIHSS), and modified Rankin scale statistics.
Two groups of patients with NIHSS scores postoperative 3 and 30 days decreased significantly compared with preoperation. NIHSS score of group A 3 and 30 days postoperation was significantly higher than group B (P < .05). Two groups of patients with GCS scores postoperative 3 and 30 days increased significantly compared with preoperation. GCS score of group A 3 and 30 days postoperation was significantly lower than group B (P < .05). Group B with vascular recanalization ratio postoperative 30 days was higher than group A, however with no significant differences (P > .05). Moreover, group B with outcomes (modified Rankin scale score ≤2 points) postoperative 3 months was better than group A, however with no significant differences (P > .05).
Solitaire AB stent embolectomy shows similar efficacy as mechanical thrombectomy in the treatment of ACI patients.
急性大脑动脉闭塞是一种常见疾病，发病率和死亡率均较高。目前，常用的机械取栓方案是机械取栓和支架取栓。然而，这两种方法的临床差异尚未完全了解。本研究旨在评估 Solitaire AB 支架取栓治疗急性脑梗死（ACI）的临床效果。
回顾性分析 2017 年 1 月至 2020 年 1 月我院收治的 96 例 ACI 患者，根据治疗方法分为 A 组（常规微导管机械取栓，n=48）和 B 组（Solitaire AB 支架取栓，n=48）。所有患者均随访 3 个月。比较两组患者术前及术后神经功能指标。采用血栓溶解治疗脑梗死量表系统、格拉斯哥昏迷量表（GCS）、美国国立卫生研究院卒中量表（NIHSS）和改良 Rankin 量表评分进行疗效评价。
两组患者术后 3 天和 30 天 NIHSS 评分均较术前显著降低，A 组术后 3 天和 30 天 NIHSS 评分均显著高于 B 组（P<0.05）。两组患者术后 3 天和 30 天 GCS 评分均较术前显著升高，A 组术后 3 天和 30 天 GCS 评分均显著低于 B 组（P<0.05）。B 组术后 30 天血管再通率高于 A 组，但差异无统计学意义（P>0.05）。此外，B 组术后 3 个月改良 Rankin 量表评分≤2 分的比例优于 A 组，但差异无统计学意义（P>0.05）。
Solitaire AB 支架取栓治疗 ACI 患者的疗效与机械取栓相似。
