IEEE J Biomed Health Inform. 2022 Jul;26(7):2929-2940. doi: 10.1109/JBHI.2022.3169325. Epub 2022 Jul 1.
In this paper, a novel denoising method for electrocardiogram (ECG) signal is proposed to improve performance and availability under multiple noise cases. The method is based on the framework of conditional generative adversarial network (CGAN), and we improved the CGAN framework for ECG denoising. The proposed framework consists of two networks: a generator that is composed of the optimized convolutional auto-encoder (CAE) and a discriminator that is composed of four convolution layers and one full connection layer. As the convolutional layers of CAE can preserve spatial locality and the neighborhood relations in the latent higher-level feature representations of ECG signal, and the skip connection facilitates the gradient propagation in the denoising training process, the trained denoising model has good performance and generalization ability. The extensive experimental results on MIT-BIH databases show that for single noise and mixed noises, the average signal-to-noise ratio (SNR) of denoised ECG signal is above 39 dB, and it is better than that of the state-of-the-art methods. Furthermore, the denoised classification results of four cardiac diseases show that the average accuracy increased above 32 % under multiple noises under SNR=0 dB. So, the proposed method can remove noise effectively as well as keep the details of the features of ECG signals.
本文提出了一种新的心电图(ECG)信号去噪方法,以提高在多种噪声情况下的性能和可用性。该方法基于条件生成对抗网络(CGAN)的框架,并对 ECG 去噪的 CGAN 框架进行了改进。所提出的框架由两个网络组成:一个生成器,由优化的卷积自动编码器(CAE)组成,一个判别器,由四个卷积层和一个全连接层组成。由于 CAE 的卷积层可以保留 ECG 信号的潜在高级特征表示中的空间局部性和邻域关系,并且跳过连接有助于在去噪训练过程中传播梯度,因此训练好的去噪模型具有良好的性能和泛化能力。在 MIT-BIH 数据库上的广泛实验结果表明,对于单一噪声和混合噪声,去噪后 ECG 信号的平均信噪比(SNR)高于 39dB,优于最先进的方法。此外,在 SNR=0dB 下,四种心脏病的去噪分类结果表明,在多种噪声下平均准确率提高了 32%以上。因此,该方法可以有效地去除噪声,同时保持 ECG 信号特征的细节。