Qiu Lishen, Cai Wenqiang, Zhang Miao, Zhu Wenliang, Wang Lirong
School of Biomedical Engineering (Suzhou), Division of Life Sciences and Medicine, University of Science and Technology of China, People's Republic of China.
Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Science, People's Republic of China.
Physiol Meas. 2021 Dec 9;42(11). doi: 10.1088/1361-6579/ac34ea.
An electrocardiogram (ECG) is an effective and non-invasive indicator for the detection and prevention of arrhythmia. ECG signals are susceptible to noise contamination, which can lead to errors in ECG interpretation. Therefore, ECG pretreatment is important for accurate analysis.The ECG data used are from CPSC2018, and the noise signal is from MIT-BIH Noise Stress Test Database. In the experiment, the signal-to-noise ratio (SNR), the root mean square error (RMSE), and the correlation coefficientare used to evaluate the performance of the network. The method proposed is divided into two stages. In the first stage, a U-net model is designed for ECG signal denoising to eliminate noise. The DR-net model in the second stage is used to reconstruct the ECG signal and to correct the waveform distortion caused by noise removal in the first stage. In this paper, the U-net and the DR-net are constructed by the convolution method to achieve end-to-end mapping from noisy ECG signals to clean ECG signals.In SNR, RMSE andindicators, U-net + DR-net proposed in this paper can achieve the best performance compared with the other five schemes (FCN, U-net etc). In the three data sets, SNR can be increased by 11.61 dB, 13.71 dB and 14.40 dB and RMSE can be reduced by 10.46 × 10, 21.55 × 10and 15.98 × 10.Despite the contradictory results, the proposed two-stages method can achieve both the elimination of noise and the preservation of effective details to a large extent of the signals. The proposed method has good application prospects in clinical practice.
心电图(ECG)是检测和预防心律失常的一种有效且非侵入性的指标。ECG信号容易受到噪声污染,这可能导致ECG解读出现错误。因此,ECG预处理对于准确分析很重要。所使用的ECG数据来自CPSC2018,噪声信号来自MIT - BIH噪声应激测试数据库。在实验中,信噪比(SNR)、均方根误差(RMSE)和相关系数用于评估网络的性能。所提出的方法分为两个阶段。在第一阶段,设计一个U - net模型用于ECG信号去噪以消除噪声。第二阶段的DR - net模型用于重建ECG信号并校正第一阶段去噪所导致的波形失真。在本文中,U - net和DR - net通过卷积方法构建,以实现从有噪声的ECG信号到干净ECG信号的端到端映射。在SNR、RMSE等指标方面,本文提出的U - net + DR - net与其他五种方案(FCN、U - net等)相比能实现最佳性能。在三个数据集中,SNR可分别提高11.61 dB、13.71 dB和14.40 dB,RMSE可分别降低10.46×10、21.55×10和15.98×10。尽管结果存在矛盾,但所提出的两阶段方法在很大程度上既能消除噪声又能保留信号的有效细节。所提出的方法在临床实践中有良好的应用前景。