Capodiferro Saverio, Limongelli Luisa, Tempesta Angela, Maiorano Eugenio, Ingravallo Giuseppe, Maffei Roberto, Favia Gianfranco
Department of Interdisciplinary Medicine, University of Bari Aldo Moro, Bari, Italy.
Department of Emergency and Organ Transplantation, University of Bari Aldo Moro, Bari, Italy, and private practice, Bari, Italy.
J Oral Implantol. 2022 Dec 1;48(6):590-594. doi: 10.1563/aaid-joi-D-21-00090.
Metastases around dental implants are extremely rare. They usually represent a secondary localization of a multiorgan metastatic neoplasm but also are, exceptionally, recognized as the first clinical manifestation of a still unknown cancer of whatever organ. Metastases usually manifest as rapidly growing lesions of hard and soft tissues and always represent a true diagnostic/therapeutic dilemma both for clinicians in choosing the more appropriate treatment and for pathologists in recognizing the primary tumor when still undiagnosed. We report 2 distinct cases of metastasis occurring around dental implants in the maxilla and mimicking peri-implantitis at the onset; more precisely, in one case, the lesion involved exclusively the alveolar bone, where an implant were previously inserted, while in the other case, a neoplasm caused bone destruction around the fixture with an impressive and rapid exophytic growth. In both cases, maxillary lesions were the first metastatic manifestation of an unknown adenocarcinoma of the lung.
牙种植体周围的转移极为罕见。它们通常是多器官转移性肿瘤的继发性定位，但也有例外，被认为是某个未知器官癌症的首例临床表现。转移通常表现为软硬组织的快速生长病变，对于临床医生选择更合适的治疗方法以及病理学家在原发性肿瘤仍未确诊时识别它来说，始终是一个真正的诊断/治疗难题。我们报告了2例在上颌牙种植体周围发生转移且起初类似种植体周炎的不同病例；更确切地说，在1例中，病变仅累及先前植入种植体的牙槽骨，而在另一例中，肿瘤导致种植体周围骨质破坏，并伴有显著且快速的外生性生长。在这两例中，上颌病变均是未知肺腺癌的首例转移表现。
