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脊髓灰质炎后综合征患者全髋关节置换术后的结局:一项匹配队列分析。

Outcomes Following Total Hip Arthroplasty in Patients With Postpolio Syndrome: A Matched Cohort Analysis.

机构信息

Department of Orthopaedics and Rehabilitation, Yale School of Medicine, New Haven, CT.

Weill Cornell Medical College, New York, NY.

出版信息

J Arthroplasty. 2022 Sep;37(9):1822-1826. doi: 10.1016/j.arth.2022.04.016. Epub 2022 Apr 18.

Abstract

BACKGROUND

Patients with postpolio syndrome (PPS) may be afflicted by hip arthritis in either the paralytic or contralateral limb. Total hip arthroplasty (THA) may be considered in these patients. However, short-term and long-term outcomes following THA in PPS patients remain poorly characterized.

METHODS

The PearlDiver MHip administrative database was queried for patients undergoing THA. Patients with a diagnosis of PPS were matched 1:4 with control patients on the basis of age, gender, and comorbidity burden. Incidence of postoperative adverse events and readmission in the 90 days following surgery and occurrence of revision arthroplasty in the five-year postoperative period were assessed between the two cohorts.

RESULTS

In total, 1,519 PPS patients were matched to 6,076 control patients without PPS. After controlling for patient demographics and comorbidities, PPS patients demonstrated higher 90-day odds of urinary tract infection (odds ratio [OR] = 1.34, P = .016), pneumonia (OR = 2.07, P < .001), prosthetic dislocation (OR = 1.63, P = .018), and readmission (OR = 1.49, P = .002). Five years following surgery, 94.7% of the PPS cohort remained revision-free, compared to 96.7% of the control cohort (P = .001).

CONCLUSION

Compared to patients without PPS, patients with PPS demonstrated a higher incidence of urinary tract infection, pneumonia, prosthetic dislocation, and hospital readmission. In addition, five-year incidence of revision arthroplasty was significantly higher among the PPS cohort. In light of these increased risks, special considerations should be made in both preoperative planning and postoperative surveillance of PPS patients undergoing THA.

LEVEL OF EVIDENCE

Level III.

摘要

背景

患有脊髓灰质炎后综合征(PPS)的患者可能会在麻痹侧或对侧肢体中患有髋关节关节炎。这些患者可能需要考虑全髋关节置换术(THA)。但是,PPS 患者接受 THA 后的短期和长期结果仍未得到充分描述。

方法

PearlDiver MHip 管理数据库中查询接受 THA 的患者。根据年龄、性别和合并症负担,将患有 PPS 的患者与对照组患者按 1:4 进行匹配。评估两组患者手术后 90 天内的术后不良事件和再入院发生率以及五年后关节翻修的发生率。

结果

共 1519 例 PPS 患者与 6076 例无 PPS 的对照组患者相匹配。在控制了患者的人口统计学和合并症后,PPS 患者在术后 90 天内发生尿路感染的几率更高(优势比 [OR] = 1.34,P =.016)、肺炎(OR = 2.07,P <.001)、假体脱位(OR = 1.63,P =.018)和再入院(OR = 1.49,P =.002)。手术后 5 年,PPS 组中有 94.7%的患者未进行关节翻修,而对照组中有 96.7%(P =.001)。

结论

与无 PPS 的患者相比,PPS 患者尿路感染、肺炎、假体脱位和住院再入院的发生率更高。此外,PPS 组中关节翻修的五年发生率明显更高。鉴于这些增加的风险,在对接受 THA 的 PPS 患者进行术前规划和术后监测时应特别考虑。

证据等级

III 级。

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