Department of Medicine, Haukeland University Hospital, 5021 Bergen, Norway.
Institute of Medical Science, University of Bergen, 5007 Bergen, Norway.
Curr Oncol. 2022 Mar 23;29(4):2193-2198. doi: 10.3390/curroncol29040178.
Basal cell carcinoma (BCC) is the most common cancer in Caucasians. It is slow growing and rarely metastasizes. If left untreated over time, invasive growth can occur. We present a patient case with a primary BCC located in the right sub-mammary area, with extensive metastases to the skeleton and bone marrow. Histopathological examination of the tumour showed BCC with a diverse growth pattern. There were no signs of local metastases. Surgery was successfully performed. Three months post-surgery the patient developed normocytic anaemia and elevated inflammation markers. [F]FDG PET/CT showed extensive FDG uptake in the entire skeleton and bone marrow. Biopsy confirmed the infiltration of BCC with similar histopathological features as the primary tumour. Prognosis of metastasized BCC is poor and, therefore, long-term follow-up of patients with risk factors is of importance.
基底细胞癌（BCC）是白种人最常见的癌症。它生长缓慢，很少转移。如果不及时治疗，可能会发生侵袭性生长。我们报告了一例位于右乳房下区域的原发性 BCC 患者，广泛转移至骨骼和骨髓。肿瘤的组织病理学检查显示 BCC 具有多种生长模式。没有局部转移的迹象。手术成功进行。术后 3 个月，患者出现正细胞性贫血和炎症标志物升高。[F]FDG PET/CT 显示整个骨骼和骨髓中摄取了大量 FDG。活检证实 BCC 浸润，其组织病理学特征与原发性肿瘤相似。转移性 BCC 的预后较差，因此，对有危险因素的患者进行长期随访很重要。
