Nast C C, Ward H J, Koyle M A, Cohen A H
Am J Kidney Dis. 1987 Jan;9(1):39-43. doi: 10.1016/s0272-6386(87)80159-2.
A 20-year-old patient with Henoch-Schönlein purpura leading to end-stage renal failure received a living-related renal transplant. She was treated with conventional immunosuppressive therapy. Following a quiescent period of 18 months pretransplant, at 3 months after engraftment there was recurrence of purpuric lesions with subsequent abdominal pain and glomerulonephritis. Renal and skin biopsies confirmed the immunopathologic changes of Henoch-Schönlein purpura. This case represents the second report of an adult with multiorgan recurrence of Henoch-Schönlein purpura following transplantation.
一名20岁患过敏性紫癜导致终末期肾衰竭的患者接受了亲属活体肾移植。她接受了传统免疫抑制治疗。移植前有18个月的静止期,移植后3个月出现紫癜性病变复发,随后出现腹痛和肾小球肾炎。肾活检和皮肤活检证实了过敏性紫癜的免疫病理变化。该病例是成人移植后过敏性紫癜多器官复发的第二例报道。