Instituto de Ingeniería, Universidad Autónoma de Baja California (UABC), Mexicali 21100, Mexico.
Facultad de Ingeniería, Universidad Autónoma de Baja California (UABC), Mexicali 21280, Mexico.
Biosensors (Basel). 2022 Mar 24;12(4):191. doi: 10.3390/bios12040191.
Lab-on-a-Chip (LoC) devices are described as versatile, fast, accurate, and low-cost platforms for the handling, detection, characterization, and analysis of a wide range of suspended particles in water-based environments. However, for gas-based applications, particularly in atmospheric aerosols science, LoC platforms are rarely developed. This review summarizes emerging LoC devices for the classification, measurement, and identification of airborne particles, especially those known as Particulate Matter (PM), which are linked to increased morbidity and mortality levels from cardiovascular and respiratory diseases. For these devices, their operating principles and performance parameters are introduced and compared while highlighting their advantages and disadvantages. Discussing the current applications will allow us to identify challenges and determine future directions for developing more robust LoC devices to monitor and analyze airborne PM.
微流控芯片(LoC)设备被描述为多功能、快速、准确且低成本的平台,可用于处理、检测、表征和分析水基环境中广泛存在的悬浮颗粒。然而,对于基于气体的应用,特别是在大气气溶胶科学中,LoC 平台很少被开发。本综述总结了新兴的用于分类、测量和识别空气传播颗粒的 LoC 设备,特别是那些被称为颗粒物(PM)的颗粒,它们与心血管和呼吸道疾病导致的发病率和死亡率上升有关。对于这些设备,介绍并比较了它们的工作原理和性能参数,同时突出了它们的优缺点。讨论当前的应用将使我们能够识别挑战,并确定开发更强大的 LoC 设备来监测和分析空气传播 PM 的未来方向。