COVID-19 Division, Wonju Public Health Center, Wonjusi 26493, Korea.
Division in Anatomy and Developmental Biology, Department of Oral Biology, Human Identification Research Institute, BK21 PLUS Project, College of Dentistry, Yonsei University, 50-1 Yonsei-ro, Seoul 03722, Korea.
Toxins (Basel). 2022 Apr 10;14(4):268. doi: 10.3390/toxins14040268.
Botulinum neurotoxin injection for treating glabellar frown lines is a commonly used method; however, side effects, such as ptosis and samurai eyebrow, have been reported due to a lack of comprehensive anatomical knowledge. The anatomical factors important for the injection of the botulinum neurotoxin into the corrugator supercilii muscle has been reviewed in this study. Current understanding on the localization of the botulinum neurotoxin injection point from newer anatomy examination was evaluated. We observed that for the glabellar-frown-line-related muscles, the injection point could be more accurately demarcated. We propose the injection method and the best possible injection sites for the corrugator supercilii muscle. We propose the optimal injection sites using external anatomical landmarks for the frequently injected muscles of the face to accelerate effective glabellar frown line removal. Moreover, these instructions would support a more accurate procedure without adverse events.
肉毒毒素注射治疗眉间竖纹是一种常用的方法；然而，由于缺乏全面的解剖知识，已经报道了一些副作用，如上睑下垂和武士眉。本研究回顾了肉毒毒素注射到皱眉肌中的解剖学因素。评估了从新的解剖学检查中对肉毒毒素注射点定位的当前理解。我们观察到，对于与眉间竖纹相关的肌肉，注射点可以更准确地标定。我们提出了皱眉肌的注射方法和最佳注射部位。我们使用外部解剖学标志提出了面部经常注射的肌肉的最佳注射部位，以加速有效的眉间竖纹去除。此外，这些说明将支持更准确的程序，而不会出现不良事件。
