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基于虚拟现实的视觉训练与 OBVAT 治疗集合不足、调节功能障碍的比较:一项先导随机对照试验。

Virtual reality-based vision therapy versus OBVAT in the treatment of convergence insufficiency, accommodative dysfunction: a pilot randomized controlled trial.

机构信息

Department of Optometry, West China Clinical Medical College, Sichuan University, 37 Guoxue Xiang, Chengdu, Sichuan Province, China.

Department of Ophthalmology, West China Hospital of Sichuan University, 37 Guoxue Xiang, Chengdu, Sichuan Province, China.

出版信息

BMC Ophthalmol. 2022 Apr 21;22(1):182. doi: 10.1186/s12886-022-02393-z.

Abstract

BACKGROUND

Virtual reality is being increasingly applied in vision therapy. However, the differences in effectiveness, optimal treatment cycle, and prognosis between virtual reality-based vision therapy and traditional therapies remain unknown. The purpose of this study was to compare the effectiveness of virtual reality-based vision therapy and office-based vergence/accommodative therapy in young adults with convergence insufficiency or accommodative dysfunction.

METHODS

The patients were randomly assigned to either the virtual reality-based vision therapy group or the office-based vergence/accommodative therapy group. The vision therapy lasted 12 weeks (1 h/week) in both groups. Binocular visual functions (vergence and accommodation) were measured and a subjective questionnaire-based assessment was performed at baseline and after 6 and 12 weeks of therapy.

RESULTS

In total, 33 patients with convergence insufficiency and 30 with accommodative dysfunction completed the study. After 12 weeks of treatment for convergence insufficiency, the Convergence Insufficiency Symptom Survey score (F = 13.704, P < 0.001), near point of convergence (F = 21.774, P < 0.001), positive fusional vergence (F = 71.766, P < 0.001), and near horizontal phoria (F = 16.482, P < 0.001) improved significantly in both groups. Moreover, the monocular accommodative amplitude (F = 22.154, P < 0.001) and monocular accommodative facility (F = 86.164, P < 0.001) improved significantly in both groups after 12 weeks of treatment. A statistically significant difference was observed in monocular accommodative facility (F = 8.140, P = 0.009) between the two groups, but not in other vergence and accommodative functions (0.098 < P < 0.687).

CONCLUSION

Virtual reality-based vision therapy significantly improved binocular vision functions and symptoms in patients with convergence insufficiency and accommodative dysfunction, thereby suggesting its effectiveness as a new optional or additional treatment for young adults with these conditions.

TRIAL REGISTRATION

This study was registered at the Chinese Clinical Trials Registry on 16/04/2019 (identifier: ChiCTR1900022556 ).

摘要

背景

虚拟现实技术在视觉治疗中应用日益广泛。然而,虚拟现实为基础的视觉治疗与传统治疗在疗效、最佳治疗周期和预后方面的差异尚不清楚。本研究的目的是比较虚拟现实为基础的视觉治疗与基于办公室的聚散和调节疗法对集合不足或调节功能障碍的年轻成人的疗效。

方法

患者被随机分配到虚拟现实为基础的视觉治疗组或基于办公室的聚散和调节疗法组。两组的视觉治疗均持续 12 周(每周 1 小时)。在基线时以及治疗 6 周和 12 周后,测量双眼视觉功能(聚散和调节)并进行主观问卷评估。

结果

共有 33 例集合不足和 30 例调节功能障碍患者完成了研究。治疗 12 周后,集合不足症状调查评分(F=13.704,P<0.001)、近点集合(F=21.774,P<0.001)、正融像性聚散(F=71.766,P<0.001)和近水平隐斜视(F=16.482,P<0.001)在两组中均显著改善。此外,两组在治疗 12 周后,单眼调节幅度(F=22.154,P<0.001)和单眼调节灵活度(F=86.164,P<0.001)也显著改善。两组间单眼调节灵活度(F=8.140,P=0.009)存在统计学差异,但在其他聚散和调节功能上(0.098<P<0.687)则无差异。

结论

虚拟现实为基础的视觉治疗显著改善了集合不足和调节功能障碍患者的双眼视觉功能和症状,提示其作为这些患者的一种新的可选或附加治疗方法的有效性。

试验注册

本研究于 2019 年 4 月 16 日在中国临床试验注册中心注册(标识符:ChiCTR1900022556)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e46/9027290/73ee0c82b45b/12886_2022_2393_Fig1_HTML.jpg

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