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基于家庭的铅笔俯卧撑疗法与基于办公室的斜视矫正疗法对集合不足症状患者的比较:一项随机对照试验。

Comparison of home-based pencil push-up therapy and office-based orthoptic therapy in symptomatic patients of convergence insufficiency: a randomized controlled trial.

机构信息

Ophthalmology Department, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, 249203, India.

Department of Community and Family Medicine, All India Institute of Medical Sciences, Rishikesh, India.

出版信息

Int Ophthalmol. 2021 Apr;41(4):1327-1336. doi: 10.1007/s10792-020-01689-7. Epub 2021 Jan 4.

Abstract

PURPOSE

To assess and compare the effectiveness of home-based pencil push-up therapy (PPT) and office-based orthoptic therapy (OBOT) in patients with convergence insufficiency.

METHODS

In this randomized clinical trial, 176 symptomatic patients with convergence insufficiency, aged between 9 to 30 years, were randomly assigned to receive 6 weeks of home-based PPT (Group I) or OBOT (Group II) after determining refractive error, near point of convergence (NPC), convergence insufficiency symptom survey (CISS) score, near phoria and positive fusional vergences (PFV) at near. The participants of Group I underwent home-based PPT (pencil push-ups exercises15 minutes per day, daily for 6 weeks) and those of Group II OBOT (convergence fusional exercises on synoptophore for 20 min per day, 3 days a week, for 6 weeks) without home reinforcement. Patients were re-examined at 3 and 6 weeks after initiation of treatment. NPC and CISS score were the primary and secondary outcome measures, respectively. Statistical analysis was performed with the independent samples t-test, Friedman test and the analysis of variance (ANOVA). Statistical significance was indicated by p-value < 0.05.

RESULTS

Participants of both the groups had statistically significant improvement in NPC, CISS score, PFV and near phoria (p < 0.001), but there was no statistically significant difference between the two groups (p > 0.05). However, patients of Group II had significantly better PFV after final visit than those of Group I (p < 0.001).

CONCLUSION

Home-based PPT with good suppression control and with compliance ensured by log book entries, is a simple, cheap, less time consuming and comparably effective alternative to more expensive OBOT for patients suffering from CI. CTRI registration number: REF/2016/11/012,732, Date of registration 25/04/ 2016, Retrospectively Registered.

摘要

目的

评估和比较家庭铅笔俯卧撑疗法(PPT)和办公室型视轴矫正疗法(OBOT)在集合不足患者中的有效性。

方法

在这项随机临床试验中,对 176 名患有集合不足症状、年龄在 9 至 30 岁之间的患者进行随机分组,分别接受 6 周的家庭 PPT(第 I 组)或办公室 OBOT(第 II 组)治疗,在确定屈光不正、近点集合(NPC)、集合不足症状调查(CISS)评分、近隐斜视和正融像性聚散(PFV)后。第 I 组的参与者接受家庭 PPT(铅笔俯卧撑练习,每天 15 分钟,持续 6 周),第 II 组的参与者在同视机上进行集合性融合练习,每天 20 分钟,每周 3 天,持续 6 周,但无家庭强化。治疗开始后 3 周和 6 周时对患者进行重新检查。NPC 和 CISS 评分分别是主要和次要结局指标。采用独立样本 t 检验、Friedman 检验和方差分析(ANOVA)进行统计分析。p 值<0.05 表示具有统计学意义。

结果

两组患者 NPC、CISS 评分、PFV 和近隐斜视均有统计学显著改善(p<0.001),但两组间无统计学显著差异(p>0.05)。然而,第 II 组患者在末次随访时的 PFV 明显优于第 I 组(p<0.001)。

结论

家庭 PPT 具有良好的抑制控制,通过日志条目确保了依从性,是一种简单、便宜、耗时更少且与更昂贵的 OBOT 相比对患有 CI 的患者具有可比性的有效替代方法。 CTRI 注册号:REF/2016/11/012,732,注册日期 2016 年 4 月 25 日,回顾性注册。

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