Bashardoust Parvaneh, Fano Benjamin J
Internal Medicine, Oceania University of Medicine, Apia, ASM.
Internal Medicine, South Texas Health System, McAllen Medical Center, McAllen, USA.
Cureus. 2022 Mar 17;14(3):e23270. doi: 10.7759/cureus.23270. eCollection 2022 Mar.
This study investigated the incidence of venous thromboembolism (VTE) in hospitalized COVID-19 patients in a community hospital in McAllen, Texas, USA. Such incidence was reported to be as high as 31% in early 2020, and in the range of 3.1%-13.6% in mid-2020, with no later studies addressing this issue. We identified a total of 47 COVID-19 hospitalized patients during August 2021, among whom four (8.5%) had a documented VTE. They were all on prophylactic anticoagulation from the time of admission, and none of them had disseminated intravascular coagulation (DIC) or a prior history of VTE. The incidence was equal between ICU and non-ICU patients. Pre-existing hypertension and cardiovascular diseases, but not high body mass index (BMI) or diabetes mellitus, appeared to be among risk factors for VTE in these patients. All four VTE patients were of Hispanic ethnicity, while only half of all 47 patients were Hispanic. The study concluded that in late 2021 the rate of VTE remained to be higher in COVID-19 than non-COVID-19 patients in hospitals despite routine and early implementation of prophylactic anticoagulation in this patient population.
本研究调查了美国得克萨斯州麦卡伦市一家社区医院中住院的新冠肺炎患者静脉血栓栓塞症(VTE)的发生率。据报道,2020年初该发生率高达31%,2020年年中在3.1%-13.6%之间,后来没有研究涉及这个问题。我们确定了2021年8月期间共47名住院的新冠肺炎患者,其中4名(8.5%)有记录的VTE。他们从入院时就都接受预防性抗凝治疗,且均无弥散性血管内凝血(DIC)或VTE病史。重症监护病房(ICU)患者和非ICU患者的发生率相同。在这些患者中,既往高血压和心血管疾病似乎是VTE的危险因素,而高体重指数(BMI)或糖尿病则不是。所有4名VTE患者均为西班牙裔,而47名患者中只有一半是西班牙裔。该研究得出结论,尽管对这一患者群体常规且早期实施了预防性抗凝治疗,但在2021年末,医院中新冠肺炎患者的VTE发生率仍高于非新冠肺炎患者。