Vermeersch Nicolas, De Fré Maxime, Verhoeven Veronique, Hunter Judith E, Tondu Thierry, Thiessen Filip E F
Department of Plastic, Reconstructive, and Aesthetic Surgery, Multidisciplinary Breast Clinic, Antwerp University Hospital, University of Antwerp, Drie Eikenstraat 655, B-2650 Antwerp, Belgium.
Department of Plastic, Reconstructive, and Aesthetic Surgery, Ziekenhuis Netwerk Antwerpen, Lindendreef 1, B-2020, Antwerp, Belgium.
JPRAS Open. 2022 Mar 11;32:182-194. doi: 10.1016/j.jpra.2022.03.001. eCollection 2022 Jun.
Age-related changes to the dorsum of the hand present as dyschromia, soft-tissue atrophy, and volume loss, resulting in wrinkles and prominent deep structures. Volume augmentation by means of autologous fat transfer (AFT) is one of the options to rejuvenate the hand; theoretically, autologous fat is the ideal filler because of durability and biocompatibility.
This systematic review aims to summarize and describe the current evidence on the technique, effectiveness, and safety of AFT in hand rejuvenation.
Three major databases, PubMed, Embase, and Web of Science, were systematically searched up to November 2020 for studies reporting on AFT and hand rejuvenation.
A total of 10 articles were included, reporting on a total of 320 patients treated by AFT to improve the aesthetic appearance of the dorsum of the hand. Some degree of postoperative oedema was present in nearly all patients. Other complications were infection (0.67%), cysts/irregularities (1.3%), temporary dysesthesia (5.3%), and ecchymosis (7%). There were no major complications. Of all patients, 97.6% self-reported to be satisfied with the result.
Overall, by combining the current evidence, AFT is considered a promising and safe technique to rejuvenate the aging hand with very high patient satisfaction. Future research, using validated patient questionnaires, objective volumetric measurements, and longer follow-up, is needed to confirm these results.
手部背部与年龄相关的变化表现为色素沉着异常、软组织萎缩和体积丧失，导致皱纹和深部结构突出。通过自体脂肪移植（AFT）进行体积增大是手部年轻化的选择之一；从理论上讲，自体脂肪由于其持久性和生物相容性，是理想的填充剂。
本系统评价旨在总结和描述AFT在手年轻化中的技术、有效性和安全性的现有证据。
截至2020年11月，对三个主要数据库PubMed、Embase和Web of Science进行了系统检索，以查找有关AFT和手部年轻化的研究报告。
共纳入10篇文章，报告了总共320例接受AFT治疗以改善手部背部美学外观的患者。几乎所有患者术后均出现一定程度的水肿。其他并发症包括感染（0.67%）、囊肿/不平整（1.3%）、暂时性感觉异常（5.3%）和瘀斑（7%）。无重大并发症。在所有患者中，97.6%自我报告对结果满意。
总体而言，综合现有证据，AFT被认为是一种有前景且安全的技术，可使衰老的手部年轻化，患者满意度非常高。需要进一步研究以验证患者问卷、客观体积测量，并进行更长时间的随访，以证实这些结果。
3级。
